Effect of Modified Poco-Poco Exercise to Aging Biomarkers in Elderly

Effect of Modified Poco-Poco Exercise to Global DNA Methylation, Growth Differentiation Factor-15, and Sarcopenia Staging in Elderly

Subject with sarcopenia get modified poco-poco exercise program for 12 weeks

34 participants (>60 years) with sarcopenia were modified poco-poco exercises three times weekly for 12 weeks will assessed sarcopenia staging (determined by assessing skeletal muscle index, muscle strength, physical performance) and levels of global DNA methylation and GDF-15.

Inclusion Criteria:

• Age above 60 years old
• Have sarcopenia (based on AWGSOP 2019 criteria)

Exclusion Criteria:

• Hearing impairment/loss hindering participants to receive verbal instructions
• Vision impairment/loss hindering participants to receive instructions
• Musculoskeletal impairment or severe joint diseases (i.e. deformity in Osteoarthritis or Rheumatoid Arthritis)
• Participants have been involved in other exercise program
• Severe cardiovascular disease diagnosed by Cardiologist.
• Participants will be excluded from the research if they skip 3 sessions of the program consecutively or skip 5 sessions cumulatively