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Subject with sarcopenia get modified poco-poco exercise program for 12 weeks
34 participants (>60 years) with sarcopenia were modified poco-poco exercises three times weekly for 12 weeks will assessed sarcopenia staging (determined by assessing skeletal muscle index, muscle strength, physical performance) and levels of global DNA methylation and GDF-15.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Modified poco-poco exercises | Experimental | Participants performed modified poco-poco exercises three times weekly for 12 weeks and were assessed, including sarcopenia staging (determined by assessing skeletal muscle index, muscle strength, physical performance) and levels of global DNA methylation and GDF-15 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Modified poco-poco exercises | Procedure | Participants performed modified poco-poco exercises three times weekly for 12 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sarcopenia Staging (Skeletal Muscle Index) | Skeletal muscle index | 12 weeks |
| Sarcopenia Staging (Muscle Strength) | Hand Grip Strength, score in kilograms | 12 weeks |
| Sarcopenia Staging (Physical Performance) | Short Physical Performance Battery, score in numerical 0-12 | 12 weeks |
| Levels of Global DNA Methylation | Global DNA methylation levels were analyzed using the ELISA-based kit | 12 weeks |
| Levels of Growth Differentiation Factor 15 | Growth Differentiation Factor 15 were analyzed the Quantikine ELISA Human GDF-15 Immunoassay | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hasan Sadikin General Hospital | Bandung | Indonesia |
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All research subjects received modified poco-poco exercise program for 12 weeks
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