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Comparing ketamine and ephedrine to decrease the incidence of post spinal hypotension after caesarean section delivery.
To compare the effect of ketamine versus ephedrine in decreasing the incidence of hypotension in caesarean section delivery a study group including 50 participants will receive ketamine and 50 group will receive ephedrine after the consent and detailed history the two groups will receive preload of 500ml enter acetate then dormicum for sedation then spinal anesthesia will be performed initial blood pressure and heart rate will be measured then every five minutes
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ketamine group | Active Comparator | 0.5mg/kg ketamine |
|
| Ephedrine group | Active Comparator | 15 mg ephedrine |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ketalar | Drug | women receiving sub-anesthetic dose of ketamine of 0.5 mg/kg IV bolus in 3 ml of normal saline. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of hypotension post spinal in CS | For ketamine Group: women receiving sub-anesthetic dose of ketamine of 0.5 mg/kg IV bolus in 3 ml of normal saline. ( Reves JG et al,2010 )
| From injection till the end of surgery |
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Inclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Basant E Mohamed, M.B.B.CH | Anesthesia resident Alain Shams University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ainshams University | Cairo | 11111 | Egypt |
All data will be shared
Before1/2026
Free
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| ID | Term |
|---|---|
| D007649 | Ketamine |
| D004809 | Ephedrine |
| ID | Term |
|---|---|
| D003510 | Cyclohexanes |
| D003516 | Cycloparaffins |
| D006840 | Hydrocarbons, Alicyclic |
| D006844 | Hydrocarbons, Cyclic |
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| Ephedrine | Drug | women receiving bolus of 15mg of ephedrine |
|
| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |
| D011412 | Propanolamines |
| D000605 | Amino Alcohols |
| D000438 | Alcohols |
| D020005 | Propanols |
| D000588 | Amines |
| D010627 | Phenethylamines |
| D005021 | Ethylamines |