Blood is considered a limited resource in health centers and blood and blood products must be kept ready. The COVID-19 pandemic has caused a significant decrease in life-saving blood donations. In addition, negative experiences such as vasovagal reactions, painful needle sticks, psychological triggers and injuries that develop during blood donation cause donors to experience anxiety, negatively affecting their vital signs and the next donation experience. Therefore, donors should be supported by distraction techniques during blood donation.

Among the techniques used to divert attention, virtual reality glasses and music applications are frequently used. It is reported that virtual reality glasses are effective in reducing anxiety and supporting vital signs and satisfaction positively because they make you feel like you are somewhere else and music has positive effects on the human soul. This study aims to determine the effect of using virtual reality glasses and music during blood donation on donors' anxiety, vital signs and satisfaction.

A single-blind randomized controlled clinical trial design with one control and two intervention groups will be used in the study. The universe of the study will consist of donors who applied to the Blood Center of Necmettin Erbakan University Faculty of Medicine Hospital between June and July 2025. The sample of the study will consist of 225 male donors who meet the inclusion criteria and agree to participate in the study. Donors will be randomly assigned to 75 Intervention-1 Group (virtual reality glasses), 75 Intervention-2 Group (music) and 75 control groups using the simple randomization method. Data will be collected through face-to-face interviews with donors using the "Descriptive Characteristics Form", "State and Trait Anxiety Scale", "Vital Findings Follow-up Form" and "Satisfaction Scale". The first researcher will act as the evaluator and the second researcher will act as the implementer in the collection of data. Thus, differences between the evaluator and the implementer will be eliminated. Donors will be shown images of nature using virtual reality glasses, donors in the other group will listen to calming music, and the control group will not receive any intervention within the scope of standard practice. The data obtained from the study will be analyzed using the SPSS 22 package program and the data will be evaluated at a 95% confidence interval and a significance level of 0.05.

Inclusion Criteria:

The criteria for inclusion in the study are as follows:

• Being between the ages of 18-60,
• Having a visual, hearing or perception disorder that prevents communication,
• Having neurological, psychiatric or psychological diseases,
• Donating whole blood.

Exclusion Criteria:

The exclusion criteria for the study are as follows:

• Having vasovagal reactions,
• Having complaints such as migraine, vertigo, active nausea, vomiting, headache,
• Not having the blood donation chair in the semi-fowler position throughout the application,
• Wanting to leave the study.