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Respiratory muscle dysfunction is a common consequence of chronic obstructive pulmonary disease (COPD).
This technique consists of placing electrodes on the skin at locations near the motor points of the diaphragm, transmitting an intermittent current, and generating action potentials capable of producing muscle contractions
Respiratory muscle dysfunction is a common consequence of chronic obstructive pulmonary disease (COPD).Weakness or fatigue of the diaphragm and accessory muscles of inspiration is widely recognized in patients on mechanical ventilation. There is increasing evidence to show mechanical ventilation itself may adversely affect the diaphragm's structure and function, which has been termed ventilator-induced diaphragmatic dysfunction. However, in patients with more severe COPD, the benefits of rehabilitation may be limited. In this context, there are new approaches to PR, such as electrical stimulation, a technique that externally stimulates contractions of peripheral muscles to improve peripheral muscle function in patients with severe COPD. This technique consists of placing electrodes on the skin at locations near the motor points of the diaphragm, transmitting an intermittent current, and generating action potentials capable of producing muscle contractions
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TEDS group will be subjected to sessions of TEDS | Active Comparator | TEDS group will be subjected to sessions of TEDS as follow : Digital electrical muscle stimulator (EV-906 Digital TENS/EMS made in TAIWAN) is applied to induce diaphragm contraction. |
|
| Non TEDS group will not be subjected to sessions of TEDS | No Intervention | Non TEDS group will not be subjected to sessions of TEDS |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Device : Digital electrical muscle stimulator is applied to induce diaphragm contraction. | Device | TEDS group will be subjected to sessions of TEDS as follow : Digital electrical muscle stimulator (EV-906 Digital TENS/EMS made in TAIWAN) is applied to induce diaphragm contraction. |
| Measure | Description | Time Frame |
|---|---|---|
| The primary outcome is the progression to invasive mechanical ventilation(IMV) | Functional assessment by US measurement of diaphragmatic excursion and thickness fraction in (cm) including base line measurement and post treatment measurement ( at the end of admission). | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| The secondary outcomes is the duration of ICU admission | The secondary outcomes is the duration of ICU admission (days), the immediate effect of TEDS and after sessions. | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mohamed AbdElmoniem, lecturer | Lecturer of chest medicine faculty of medicine Mansoura university | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of medicine mansoura university | Al Mansurah | 35516 | Egypt |
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Effect of trans-cutenuous electrical diaphragmatic stimulation on severe chronic obstructive pulmonary disease exacerbation
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Participants will be randomly assigned into a TEDS group or control group. Method of randomization : Before participant recruitment, sequential sealed envelopes are prepared by an independent investigator, with one envelope will be chosen randomly by another investigator for each participant.
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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