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This study investigates epigenetic changes in menstrual effluent and plasma from women with endometriosis to identify potential non-invasive diagnostic biomarkers for the disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Epigenetics characterization | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endometrial biopsy or menstrual cup and blood sample | Procedure | Enrolled patients will give their menstrual effluent either via a menstrual cup or via a pipelle biopsy. They will also undergo a blood draw. |
| Measure | Description | Time Frame |
|---|---|---|
| Epigenetic analysis | Histone post-translational modifications | Throughout the entire study, approximately during 3,5 years |
| Epigenetic analysis | miRNA | Throughout the entire study, approximately during 3,5 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marie-Madeleine Dolmans, MD, PhD | Contact | +32 (0)2 764 5287 | marie-madeleine.dolmans@uclouvain.be |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cliniques universitaires Saint-Luc | Recruiting | Brussels | 1200 | Belgium |
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D052576 | Menstrual Hygiene Products |
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D053566 | Feminine Hygiene Products |
| D004864 | Equipment and Supplies |
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
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| D000091662 | Genital Diseases |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |