Effectiveness of Intranasal Dexmedetomidine Premedication in Child Intubation

Effectiveness of Adjuvant Premedication of Intranasal Dexmedetomidine on the Intubation Procedure in Children

The purpose of this study is to find out if a medicine called dexmedetomidine, given as a nasal spray, can help patients stay calm and comfortable before having a breathing tube placed (intubation). Researchers want to see if using this nasal spray affects blood pressure, heart rate, comfort with the oxygen mask, how quickly the tube is placed, and how sleepy patients become. They also want to check if patients who receive dexmedetomidine need less pain medicine (Fentanyl) during the procedure. Participants will receive either the dexmedetomidine nasal spray or a plain saltwater spray (placebo). Doctors will then measure blood pressure, heart rate, comfort levels, time needed for intubation, sleepiness, and the amount of pain medication used.

Inclusion Criteria:

• Children aged 1-6 years undergoing elective surgery
• ASA physical status 1 and 2

Exclusion Criteria:

• Children with difficult airway
• Active infection in nasal and oral area
• Subjects with mental retardation, ADHD, and cerebral palsy
• Difficult intravenous access