The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis

Efficacy of Quercetin Loaded on Chitosan Nanoparticles Gel as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis: Randomized Controlled Clinical Trial

the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients

the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients not having systemic diseases.the 2ry aim of study to estimate the neacular factor kabba B level in gingival crevicular fluids.

Inclusion Criteria:

- Patients of both sexes with an age ranging between 25 and 55 years will be included in the study. Patients diagnosed as having periodontitis based on clinical and radiographic examinations will be included

Exclusion Criteria:

• Insulin dependent diabetes
• Thyroid disease
• Patients with sensitivity to the medication used in the study
• patients with a history of antibiotic use or anti-inflammatory drugs during the previous 3 months prior to the study will be excluded from the study.
• Additionally, patients with systemic diseases, smokers, pregnant and lactating patients, and patients not compliant with oral hygiene procedures will also be excluded