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In this cross-sectioanl study, 90 patients aged >12 years old with T1DM who are on MiniMed 780G system will be included.The investigators aim to assesse the association of patients' adherence to Mediterranean diet (MD) with CGM and insulin metrics, as well as anthropometric measurements, BMI, lipid levels and blood pressure.Moreover, markers of endothelial, cardiovascular and liver function will be also assessed and associated with the use of Minimed 780G and the adherence to MD.
This cross-sectional study will include 90 participants, children adolescents and young adults (12> years old) with T1D that are on MiniMed 780G system. Participants will be evaluated for adherence to Meditteranean Diet (MD) with PREDIMED questionnaire. HbA1c, CGM and Insulin Metrics, anthropometric measurements, blood pressure and lipid leves will be aso evalutaed. Markers of endothelial cardiovascular and liver function will also be assessed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Type 1 Diabetes Mellitus | patients aged >12 years old with T1DM who are on MiniMed 780G |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Minimed 780G | Device | patients aged >12 years old with T1DM who are on MiniMed 780G |
|
| Measure | Description | Time Frame |
|---|---|---|
| Time in Range | Assessment of time in range | Baseline |
| Time below range | Assessment of time below range | Baseline |
| Time above range | Assessment of time above range | Baseline |
| Basal Insulin dose | Assessment of basal insulin doses | Baseline |
| Correction Insulin dose | Assessment of correction insulin dose | Baseline |
| Pulse wave velocity | Assessment of pulse wave velocity | Baseline |
| Endothelial glycocalyx | Assessemnet of the thickness of endothelial glycocalyx | Baseline |
| Global longitudinal strain | Assessment of global longitudinal strain. | Baseline |
| E score | Assessement of E score and CAP score. | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
Diabetic Ketoacidosis in the 6 months prior to screening visits
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Children adolescents and young adults (12> years old) with T1D that are on MiniMed 780G system.
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| Name | Affiliation | Role |
|---|---|---|
| Vaia Lambadiari | Attikon General University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Attikon University General Hospital | Chaïdári | 124 62 | Greece |
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| ID | Term |
|---|---|
| D003922 | Diabetes Mellitus, Type 1 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Assessment of CAP score | CAP score | Baseline |
| MED diet | Assesment of Adherence to MED diet | Baseline |
| Fat mass | Assessment of fat mass | Baseline |
| Lean Mass | Assessment of lean mass | Baseline |
| D004700 | Endocrine System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |