Explore the Therapeutic Effect of Theta Burst Stimulation on Emotion Regulation in Autism With Minimally Verbal Ability or Intellectual Disability

Explore the Therapeutic Effect of Theta Burst Stimulation on Emotion Regulation in Autism With Minimally Verbal Ability or Intellectual Disability

The investigator would like to investigate the impact of theta-burst stimulation over left DLPFC in autism with minimally verbal ability or intellectual disability

Inclusion Criteria:

• Diagnosis of autism spectrum disorder, confirmed by DSM-5.
• Individuals with minimal verbal ability or intellectual disability (FSIQ < 70).

Exclusion Criteria:

• Current or past severe neurological disorders, such as epilepsy, or significant visual or hearing impairments.
• Current or past severe systemic diseases, such as cardiovascular disease, diabetes, or multiple sclerosis.
• History of severe brain injury.
• Presence of implanted metal devices, such as a pacemaker or medication pump.
• Current or past severe psychiatric disorders, such as schizophrenia, bipolar disorder, or major depressive disorder.
• Pregnancy.
• Significant brain abnormalities, such as intracranial space-occupying lesions.
• Family history of epilepsy.
• History of febrile seizures.
• Concurrent use of medications that increase the risk of seizures.
• Sleep disorders during rTMS procedures.
• Skin lesions or trauma at the stimulation site.
• Deemed ineligible by the principal investigator (PI).
• Participation in another clinical trial within the past month.
• Suicidal ideation or suicide attempts within the past year.