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This study aimed to identify predictive factors associated with the achievement of pentafecta outcomes following partial nephrectomy.
Partial nephrectomy (PN) is widely considered the preferred treatment for clinical T1 (cT1) renal masses, primarily because it preserves kidney function more effectively than radical nephrectomy.
The trifecta metric includes three components: warm ischemia time (WIT) of ≤ 25 minutes or cold ischemia time (CIT) of ≤ 60 minutes, negative surgical margins, and the absence of perioperative major complications. The pentafecta expands upon these criteria by adding two additional parameters: preservation of ≥ 90% of the estimated glomerular filtration rate (eGFR) and no progression in chronic kidney disease (CKD) stage within 12 months postoperatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Open Partial Nephrectomy | Experimental | Patients underwent open partial nephrectomy. |
|
| Laparoscopic Partial Nephrectomy | Experimental | Patients underwent laparoscopic partial nephrectomy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Open Partial Nephrectomy | Procedure | Patients underwent open partial nephrectomy. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Predictor of pentafecta achievement | Predictor of pentafecta achievement, such as smoking index, was recorded. | 12 months postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Amount of blood loss | Amount of blood loss was recorded. | Intraoperatively |
| Surgery duration | Surgery duration was recorded. | Intraoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| South Valley university | South Valley | Qena Governorate | 83523 | Egypt |
The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
After the end of study for one year.
The data will be available upon a reasonable request from the corresponding author.
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| ID | Term |
|---|---|
| D002292 | Carcinoma, Renal Cell |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| Laparoscopic Partial Nephrectomy | Procedure | Patients underwent laparoscopic partial nephrectomy. |
|
| Length of hospital stay | Length of hospital stay was recorded from admission till the discharge from hospital. | Till discharge from hospital (Up to one week). |
| Intraoperative complications | Intraoperative complications were recorded. | Intraoperatively |
| Degree of pain | Each patient will be instructed about postoperative pain assessment with the visual analog scale (VAS). VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). | 24 hours postoperatively |
| Analgesic requirements | Incidence of required analgesic was recorded. | 24 hours postoperatively |
| Incidence of complications following surgery | Incidence of complications following surgery were recorded. | 12 months postoperatively |
| D009369 | Neoplasms |
| D007680 | Kidney Neoplasms |
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |