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| Name | Class |
|---|---|
| Fundação de Amparo à Pesquisa do Estado de São Paulo | OTHER_GOV |
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Partial nephrectomy is considered the standard treatment for renal tumors smaller than 7 cm. With the evolution of image diagnostic tools and dissemination of its use, smaller tumors are being commonly diagnosed and treated. The partial open nephrectomy is still considered the gold standard technique for nephron sparing surgery, especially when the surgeon is not experienced with the minimally invasive surgery. In the last 15 years, uncountable minimally invasive techniques were developed, including the laparoscopic partial nephrectomy. The objective of this study is compare the partial laparoscopic nephrectomy to open partial nephrectomy in terms of perioperative, oncologic and functional outcomes. A balanced randomized prospective trial will be conducted. One group of patients will be submitted to to open partial nephrectomy while the other group of patients will be submitted to laparoscopic partial nephrectomy. A randomized prospective trial comparing the two techniques is necessary to determine the differences in outcomes between them and if the laparoscopic partial nephrectomy can be performed without harms to the patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Laparoscopic Partial Nephrectomy | Experimental | Patients with kidney neoplasms submitted to laparoscopic partial nephrectomy |
|
| Open Partial Nephrectomy | Active Comparator | Patients with kidney neoplasms submitted to open partial nephrectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Partial nephrectomy | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Surgical Complications | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Renal Function | 2 years | |
| Oncological outcomes | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sanarelly P Adonias, Study Coordinator | Contact | + 55 11 3893-2528 | enfpesq2.urousp@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Marcos F Dall'Oglio, M.D., Associate Professor | Cancer Institute of the State of São Paulo - University of Sao Paulo | Study Director |
| Giuliano B Guglielmetti, Doctor | Cancer Institute of the State of São Paulo - University of Sao Paulo |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cancer Institute of the State of São Paulo | Recruiting | São Paulo | 01246-000 | Brazil |
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| ID | Term |
|---|---|
| D007680 | Kidney Neoplasms |
| D002292 | Carcinoma, Renal Cell |
| ID | Term |
|---|---|
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| Alexandre C Sant'Anna, Doctor | Cancer Institute of the State of São Paulo - University of Sao Paulo | Study Chair |
| D052776 |
| Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |