Prone Positioning in ARDS: Predicting Neurological Complications Via Cerebral Hemodynamics

Changes in Cerebral Blood Flow Before and After Prone Position in Patients With ARDS Predict the Occurrence of Neurological Complications

Prone Positioning in ARDS: Predicting Neurological Complications via Cerebral Hemodynamics

Collecting Medical Records, Demographic Characteristics, and Clinical Data of Moderate to Severe ARDS Patients Requiring Prone Positioning Treatment at Chengdu Pixdu District People's Hospital, Sichuan Provincial People's Hospital, The Fourth People's Hospital of Chengdu, and Chengdu Shuangliu District First People's Hospital from March 2025 to March 2026.

Inclusion Criteria:

• Age≥18 years
• Meet the diagnostic criteria for ARDS(Acute Respiratory Distress Syndrome),with PaO₂/FiO₂<150 mmHg,and requiring prone ventilation
• Expected duration of mechanical ventilation>48 hours
• Written informed consent obtained

Exclusion Criteria:

• Presence of contraindications to prone positioning(e.g.,head and neck injuries,spinal instability,severe intracranial hypertension)
• Severe neurological diseases(e.g.,cerebral hemorrhage,cerebral infarction,intracranial space-occupying lesions)that may affect the monitoring of cerebral hemodynamics
• Life-threatening ARDS
• Patients who are unable to undergo neurological assessment
• Poor image quality or absence of images