Prone Positioning for Brain-injured Patients With Severe ARDS (ProBrain)

Prone Positioning for Brain-injured Patients With Severe ARDS (ProBrain)

Prone position (PP) is a key component to treat hypoxemia in patients with severe acute respiratory distress syndrome (ARDS). However, most studies evaluating PP effects in patients with ARDS exclude those with brain-injuries without providing any medical evidence. This prospectice observational study aimed to investigate if prone positioning leads to significant modification of cerebral perfusion in brain-injured patients with ARDS.

Inclusion Criteria:

• adult's patients suffering from brain injuries
• patients neurologically monitored with TCD
• patients requiring prone position for severe ARDS

Exclusion Criteria:

• pregnant women
• patients with contrindication to prone position