Predictors of Physical Activity in Adult Patients With Hemophilic Arthropathy

Predictors of Physical Activity in Adult Patients With Hemophilic Arthropathy. A Multicenter Cross-sectional Cohort Study

Introduction. The development of hemophilic arthropathy causes degenerative joint damage that leads to functional impairment, limiting physical activity and causing disability in patients with hemophilia.

Objectives. i) To assess the level of physical activity in patients with hemophilia; ii) To identify the best predictive model for physical activity in adult patients with hemophilic arthropathy.

Material and method. Multicenter cross-sectional cohort study. Eighty-eight patients will be recruited. The dependent variable will be physical activity (International Physical Activity Questionnaire). Secondary variables will be kinesiophobia (Tampa Kinesiophobia Scale), functionality (Functional Independence Scale in Hemophilia), pain intensity, and clinical, anthropometric, and sociodemographic variables.

Inclusion Criteria:

• Patients with hemophilia A or B
• Over the age of majority
• With a medical diagnosis of severe phenotype of the disease
• With a medical diagnosis of hemophilic arthropathy in the lower limbs
• Under on-demand or prophylactic drug treatment.

Exclusion Criteria:

• Patients who require technical aids for walking
• Patients who are dependent for activities of daily living
• Patients over the age of 60
• Patients with cognitive impairments that prevent them from understanding the questionnaires