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The Aim of the study is to evaluate Accuracy of automated mandibular defect reconstruction using Artificial intelligence and assessing impact on aesthetic and occlusion outcomes using patient-specific reconstruction plates.
The digital surgical process often requires an expected mandibular reference model. Currently, the common digital surgery process, is to mirror repair or manually look for other similar mandibles for local data fusion and smoothing processing. A more accurate expected reference model is difficult to achieve, time consuming and difficult to promote in clinical practice. Moreover, rapid routing processing often has poor accuracy. For cumulative bilateral lesions, massive lesions, obvious displacement or lesions cross the middle line, there is still no effective method to predict the expected reference model in clinical practice.
The main objective for conducting this study is to propose an improved algorithm to overcome the drawbacks of recent studies using 3D Unet and to test the predictability and clinical value of virtually generated 3d models of defected mandible in real patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient specific reconstruction plates | Experimental | Patients with benign lesions indicated for resection and resulting in mandibular continuity defects treated with patient specific reconstruction plates. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| patient specific reconstruction plates | Procedure | Use of patient specific reconstruction plates on the 3-D virtually-generated defect using Artificial Intelligence. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy Of the virtually Generated 3D model using AI | The measuring device is the AI model using the Percentage as a unit | baseline |
| Accuracy of AI generated model clinically | The measuring device is by Superimposition of both virtual 3-d generated model and real patient CT post operative using software ( blender ) . ( Structural Similarity Index) (SSIM) | baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Aethetic outcome | The measuring device is Facial appearance using a 4-point score | baseline |
| Occlusion | The measuring device is Digital occlusion analysis using T-scan and the unit is percentage |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sarah Moustafa. Moustafa, MSc. | Contact | 56794540 | sarah.elayoutti@dentistry.cu.edu.eg | |
| Sarah Moustafa. Moustafa, PHD | Contact | 01006133135 | waleed.elbeialy@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Sarah Moustafa, MSc. | Cairo University | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33009429 | Background | Liang Y, Huan J, Li JD, Jiang C, Fang C, Liu Y. Use of artificial intelligence to recover mandibular morphology after disease. Sci Rep. 2020 Oct 2;10(1):16431. doi: 10.1038/s41598-020-73394-5. | |
| 30115476 | Background | van Baar GJC, Forouzanfar T, Liberton NPTJ, Winters HAH, Leusink FKJ. Accuracy of computer-assisted surgery in mandibular reconstruction: A systematic review. Oral Oncol. 2018 Sep;84:52-60. doi: 10.1016/j.oraloncology.2018.07.004. Epub 2018 Jul 20. |
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| ID | Term |
|---|---|
| D008339 | Mandibular Neoplasms |
| ID | Term |
|---|---|
| D007573 | Jaw Neoplasms |
| D012888 | Skull Neoplasms |
| D001859 | Bone Neoplasms |
| D009371 | Neoplasms by Site |
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| baseline |
| D009369 |
| Neoplasms |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D007571 | Jaw Diseases |
| D008336 | Mandibular Diseases |
| D009057 | Stomatognathic Diseases |