How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study

The Impact of Bleeding on Delirium Outcomes in Older Patients With Hip Fractures: A Single-Blind, Randomized Controlled Trial - The IMPROVE-HIP Study

The goal of this clinical trial is to investigate whether early detection of bleeding and prompt blood transfusions can help prevent delirium in patients aged 75 and older who are admitted to the hospital with hip fractures. The main question the trial aims to answer is:

Do patients aged 75 and older with hip fractures benefit from earlier treatment of anemia (low blood count) to reduce the risk of delirium?

Researchers will compare early diagnosis and treatment of bleeding with standard care to determine if it helps lower the risk of developing delirium.

Participants will:

Undergo blood tests, have their vital signs monitored, and be screened for delirium three times a day for the first 48 hours after surgery.

Receive blood transfusions promptly if their hemoglobin levels fall below a specified threshold.

Attend a follow-up visit at 30 days to assess cognitive function and overall quality of life.

Attend another follow-up at 90 days to evaluate hospital readmissions and survival.

Inclusion Criteria:

• Hip fracture

Exclusion Criteria:

• Pathological hip fracture
• Periprosthtic fracture
• Unable to speak or understand Danish
• Does not wish to recieve blood transfusion
• If the investigator finds the patient unable to cooperate to the study (e.g. in case of severe dementia and externalizing behaviour)