Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of Mandibular Extracted Molars

Comparison of the Effect of Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of Mandibular Extracted Molars ( a Randomised Controlled Clinical Trial) Comparison of the Effect of Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of Mandibular Extracted Molars ( a Randomised Controlled Clinical Trial)

Different materials and techniques are employed for socket preservation to reduce the alveolar bone resorption in both the horizontal and vertical dimensions as well as the soft tissue collapse after tooth extraction. Because of the repair abilities of the growth factors and proteins released by platelets, the development and application of platelet-enriched preparations have revolutionised the area of regenerative medicine.The present study will be designed to study the difference between A-PRF and IPRF with the addition of Xenograft in the preservation of bone in mandibular molars.

Inclusion Criteria:

• Patients who need extraction of hopeless mandibular molars
• Teeth with advanced caries not amenable for conservative treatment
• Patients who are willing and fully capable of complying with the study protocol.

Exclusion Criteria:

• Systemic diseases that prevent surgery
• Acute or chronic oral infections
• Periodontal diseases
• Heavy smokers or alcoholics
• On anticoagulant drugs.
• Pregnancy
• History of radiotherapy or chemotherapy of the head and neck region