Multimodal Ophthalmic Imaging and Plasma Biomarkers for the Early Detection of Alzheimer's Disease

Multimodal Ophthalmic Imaging and Plasma Biomarkers for the Early Detection of Alzheimer's Disease

With the accelerating global aging population, dementia has become a pressing worldwide issue. This project aims to identify specific plasma biomarkers and ocular indicators for the early detection of Alzheimer's disease (AD).

Inclusion Criteria:

• Male or female participants aged ≥ 50 years;
• Participants diagnosed with Alzheimer's Disease (AD), mild cognitive decline (MCI), subjective cognitive decline (SCD), or cognitively normal (CN);
• Signed informed consent form

Exclusion Criteria:

• Presence of other neurological disorders and systemic diseases that may cause cognitive impairment;
• Inability to cooperate with cognitive assessments;
• Refusal to undergo blood sampling.