Study of Auditory Perception After Progressive Exposure to Aversive Sounds in People With Misophonia

ClinicalTrials.gov ID

NCT06921187

Lead Sponsor

Institut PasteurINDUSTRY

Overall Status

Not yet recruiting

Study Type

Interventional

Phase

Not Applicable

Enrollment

110Estimated

Last Update Posted

Apr 10, 2025Actual

Start Date

Jun 2025Estimated

Primary Completion Date

Mar 2026Estimated

Completion Date

Mar 2026Estimated

Official Title

Etude de la Perception Auditive après Exposition PROgressive Aux Sons Aversifs Chez Des Personnes MISophonEs

Brief Summary

The primary objective of the project is to characterise and measure the auditory perception of subjects with misophonia compared with the auditory perception of control subjects.

• Misophonia

• Psychoacoustic test
• semi-structured interviews
• Exposure to unpleasant sounds

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

Yes

Eligibility Criteria

Inclusion Criteria:

For all participants

• Obtain oral consent from the participant after receiving information about the study,
• Be 18 years or older on the day of inclusion,
• Be fluent in French (spoken and written),
• Have no known hearing loss, verified by pure tone audiometry.
• Declare that they do not have tinnitus,
• Declare that they do not have hyperacusis, verified by measuring discomfort thresholds.
• Be affiliated to the social security or equivalent scheme.

For participants with misophonia:

- Declare discomfort, reduced tolerance to specific sounds (mouth noises, throat clearing, breathing, etc.).

Exclusion Criteria:

• Bear the after-effects of an ear infection and/or have a history of an ENT disease that permanently affects hearing or balance (vestibular schwannoma, Ménière's disease, sudden or fluctuating deafness, congenital hypoacusis),
• Be under guardianship,
• deprived of liberty by judicial or administrative decision, or subject to legal protection.

Primary Purpose

Basic Science

Allocation

Non-Randomized

Interventional Model

Parallel Assignment

Masking

None (Open Label)

Lead Sponsor

Institut PasteurINDUSTRY

Collaborators

Institut de l'AuditionOTHER

paul.avan@pasteur.fr+331 76 53 50 93

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