Lupine Allergy in Children

Lupine Allergy in Children: Relevance of Sensitization and Severity of Reaction

All children sensitized to lupine who have performed an oral food challenge (OFC) to lupine between January 2017 and May 2024 in the Pediatric Allergy Unit of the University Hospital of Nancy were included. Retrospective data regarding food and respiratory allergies were collected as well as information regarding lupine skin prick test (SPT), specific IgE (sIgE) and OFC. Severity of allergic reaction was evaluated by CoFAR grade and reactogenic cumulative threshold dose.

Aims of this study were (i) to assess relevance of sensitization to lupine in children and (ii) to describe severity of reactions in case of allergy.

Inclusion Criteria:

• cutaneous or biological sensitization to lupine

Exclusion Criteria:

• oral food challenge done with something other than lupine flour