The Effect of Probiotics on Gums Health and Bad Breath

Evaluating The Effect of Probiotics on Oral Health Status and Its Influence on The Gingival Disease and Halitosis in Iraq

the study is about using healthy bacteria to improve the overall gingival and overall health and prevent or decrease the bad odor of the mouth caused by bad bacteria

The goal of this study is to verify the effect of Probiotics on oral Health Status and eliminate the gingival disease and Halitosis by measuring the levels of salivary biomarkers (cytokine IL-1b and proteases Matrix metalloproteinase (MMP-8) in saliva) and level of volatile sulfur compounds (VSCs) and their effects on improving gingival diseases clinical parameters in person age of (17-25) years old. The participants are randomly divided into two parallel groups (A, B). Group A will take probiotics and group B will take placebo for 28 days. The levels of IL-1b, MMP-8 in saliva, and VSCs measurement will be recorded respectively in different intervals of zero time and repeated on 14 days and 28 days.

Statistical analysis will be done then comparative between two groups

The Inclusion criteria

• Subjects (male and female) between the age range 17-25 years old.
• Subjects with mouth breathing habit.
• Subjects with orthodontic and prosthodontic appliance
• Race from Iraq.
• Subjects having a dentition with ≥20 evaluable teeth (minimum of five teeth per quadrant).

The Exclusion criteria

• History of chronic disease.
• History of systemic disease.
• Patients with autoimmune diseases.
• Patients under antibiotic treatment.
• Pregnant, lactating females.
• History of undergoing nonsurgical and surgical periodontal therapy in the last 6 months.