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| Name | Class |
|---|---|
| University Grenoble Alps | OTHER |
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Total knee arthroplasty remains the gold standard in the management of disabling gonarthrosis. Improved functional results, increased availability of care and an ageing population have all contributed to the rise in total knee replacement surgery in Western countries. Surgical techniques have been steadily improving for several decades in terms of implant positioning and joint alignment. However, 10% of patients are dissatisfied with the clinical and functional results. The challenge is to understand why these patients remain dissatisfied despite these surgical advances. Our aim is to understand the functional impact of knee prosthesis through a quantified analysis of gait, the performance of certain tasks of daily living, and pre- and post-operative proprioceptive assessments. We will link these results with patient feedback to identify factors potentially responsible for poor postoperative outcomes.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Quantitative Gait Analysis | Other | The following explorations will be carried out pre-operatively (pre-OP), then post-operatively at 3 months (post-OP3) and 12 months (post-OP12) :
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| Measure | Description | Time Frame |
|---|---|---|
| Post-operative functional recovery of patients who have undergone total knee arthroplasty for gonarthrosis by analyzing their locomotion ability | The primary endpoint is a composite endpoint assessed by quantified gait analysis (QGA) : 1/ Gait speed 2 / Step length | Preoperatively (PreOP) and 12 months postoperatively (PostOP12) |
| Measure | Description | Time Frame |
|---|---|---|
| Functional recovery by analyzing changes in gait variability | Functional recovery is assessed by quantified gait analysis (QGA) : Measurement of step length Measurement of step width Measurement of cycle time Measurement of step speed and cadence Measurement of gait variability and stability parameters | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients who undergone total knee arthroplasty for gonarthrosis in Grenoble University Hospital
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Grenoble University Hospital | Grenoble | 38043 | France |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
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| Impact of total knee arthroplasty (TKA) on proprioception | Proprioception is assessed by Joint Position Sense (JPS) test : Error between target angle and established angle: average absolute error in relation to the target angle in degrees. This will enable us to obtain an average absolute error for the three trials for each target angle per lower limb and per patient. | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Functional recovery after TKA by analyzing changes in daily living tasks by SIT TO STAND test | Measurement of displacements of the center of pressure and gravity, angular velocities (trunk, knee, hip, ankle), hip and knee angular moments, ground reaction force (for each lower limb). | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Functional recovery after TKA by analyzing changes in daily living tasks by STEP INITIATION test | Analysis of ground reaction force on healthy side vs. pathological side during ascent and descent of step, knee joint amplitudes in flexion during ascent and descent of step. | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Functional recovery after TKA by analyzing changes in daily living tasks by OBSTACLE CLEARANCE test |
| Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Evolution of Quality of Life | EQ5D-5L questionnaire | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Evolution of the patient's functional results assessed by the KSS questionnaire | The KSS is a functional questionnaire (e.g. questions on pain, joint amplitude, possible walking distance) completed by the patient and the surgeon. | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Evolution of the patient's functional results assessed by the SKV questionnaire | The SKV score is a very simple functional score, based on a single question: "How would you rate your knee on the day of the examination, compared with a normal knee in percentage terms?" completed by the patient. | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| Evolution of the patient's functional results assessed by the KOOS questionnaire | KOOS is a questionnaire assessing knee function, pain and impact on daily life score to be completed exclusively by the patient. The questionnaire comprises five dimensions: symptoms, stiffness, pain, function of daily life and activities, sports and leisure. | Preoperatively (PreOP) , 3 months postoperatively (PostOP3), 12 months postoperatively (PostOP3) |
| D012216 |
| Rheumatic Diseases |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |