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Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in terms of bone quantity?
Soft tissue dehiscence could result due to flap irritation as a result of, closure under tension, intraoperative or postoperative recipient site infection, postoperative edema, which in turns compromises stability of onlay bone blocks thus osseintegration of bone block. Any attempt of bone recontouring and resuturing fails since there is no vascular bed. Ideal requirements of barrier membranes are, they should be biological compatible, they must act as a barrier membrane, unwanted fibroblasts should be hindered from entrance while allowing diffusion of nutrients, tissue integration (biological adhesion), tissues should be able to grow into the membrane but not through it. Space maintainer, it should be sufficiently stiff, so as not to collapse into the underlying particulate bone under the pressure of soft tissue and it should be ease in its manipulation, adaptation and handling, as for example, collagen membrane. Some types of collagen membrane, contain some degrees of stretchability example Geistlich Bio-Gide or Jason Membrane Botiss.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study Group A: Retromolar bone block covered with collagen membrane. | Experimental | The onlay bone block harvested from retromolar region and fixed with micro screws, a mixture of autogenous and xenogenic particulate bone graft is going to be packed in between the bone block and recipient site. The assembly is going to be covered with native collagen membrane and fixed with titanium bone tacks. |
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| Control Group B: Retromolar bone block without collagen membrane. | Active Comparator | The onlay bone block harvested from retromolar region and fixed with micro screws, a mixture of autogenous and xenogenic particulate bone graft is going to be packed in between the bone block and recipient site. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Onlay bone block covered with collagen membrane | Procedure | Onlay bone block covered with collagen membrane |
|
| Measure | Description | Time Frame |
|---|---|---|
| Quantity of bone gain. | Measured using linear measurements from Cone Beam Computed Tomography in millimeters. | At 5 months from ridge augmentation. |
| Measure | Description | Time Frame |
|---|---|---|
| Soft Tissue Dehiscence | Exposure of bone block assembly and impaired healing | Baseline 1st Week. Written Binary Numerical Yes or No. |
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Inclusion Criteria:
Exclusion Criteria:
• Heavy smokers more than 20 cigarettes per day.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mohannad A. Ismail, MSc. | Contact | 01222968444 | +20 | mohannadahmed@hotmail.com |
| Niveen A. Askar, PhD | Contact | 01001558769 | +20 | niveen.askar@dentistry.cu.edu.eg |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry Cairo University | Recruiting | Cairo | 11553 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12950840 | Background | Hammerle CH, Jung RE. Bone augmentation by means of barrier membranes. Periodontol 2000. 2003;33:36-53. doi: 10.1046/j.0906-6713.2003.03304.x. No abstract available. | |
| Background | Cash and Alex: 20 years of guided bone regeneration in implant dentistry, 2nd ed. (2009). | ||
| Background | Urban, I A., Nagrusky H, Lozada JM: | ||
| Background | Urban, I A., Nagrusky H, Lozada JM.: | ||
| 26759078 |
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| Onlay bone block without collagen membrane | Procedure | Onlay bone block covered without collagen membrane |
|
| Background |
| Pellegrino G, Lizio G, Corinaldesi G, Marchetti C. Titanium Mesh Technique in Rehabilitation of Totally Edentulous Atrophic Maxillae: A Retrospective Case Series. J Periodontol. 2016 May;87(5):519-28. doi: 10.1902/jop.2016.150432. Epub 2016 Jan 12. |
| 31308978 | Background | Polis-Yanes C, Cadenas-Sebastian C, Gual-Vaques P, Ayuso-Montero R, Mari-Roig A, Lopez-Lopez J. Guided Bone Regeneration of an Atrophic Maxilla Using Heterologous Cortical Lamina. Case Rep Dent. 2019 Jun 11;2019:5216362. doi: 10.1155/2019/5216362. eCollection 2019. |
| 1955919 | Background | Jensen J, Sindet-Pedersen S. Autogenous mandibular bone grafts and osseointegrated implants for reconstruction of the severely atrophied maxilla: a preliminary report. J Oral Maxillofac Surg. 1991 Dec;49(12):1277-87. doi: 10.1016/0278-2391(91)90303-4. |
| 11117684 | Background | Montazem A, Valauri DV, St-Hilaire H, Buchbinder D. The mandibular symphysis as a donor site in maxillofacial bone grafting: a quantitative anatomic study. J Oral Maxillofac Surg. 2000 Dec;58(12):1368-71. doi: 10.1053/joms.2000.18268. |