Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain

Effect of Intentional Extrusion of an Intracanal Corticosteroid Solution on Post Endodontic Treatment Pain: a Randomized Clinical Trial

The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis (SIP/SAP). The main question it aims to answer: Is there an analgesic effect of extruding an intracanal solution of DXA into the periapical tissues in patients diagnosed with SIP/SAP? Researchers will compare dexamethasone to a placebo to see if the extrusion dexamethasone works in reducing post-endodontic treatment pain.

Inclusion Criteria:

• A diagnosis of irreversible pulpits with symptomatic apical periodontitis
• Adult patients (aged 18 - 70)
• Healthy patients or those with a well-controlled disease (ASA I & II)

Exclusion Criteria:

• A diagnosis of necrotic pulp, or normal apical tissues
• Patients with a severe systemic disease (ASA III or higher)
• Patients who received analgesics12 hours before presentation
• Previously treated/initiated Endodontics treatment on the same tooth
• Unopposed teeth
• Third molar teeth
• Non-restorable teeth
• Periodontally compromised teeth
• Pregnant or lactating patients