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assessment of the level of interleukin 4 (IL-4) in the lesional skin and serum of PLC patients and compare its level with healthy controls.
measuring the level of Interleukin 4 in lesional skin and it's serum level using ELIZA in patients with Pityriasis lichenoides chronica and comparing the levels with healthy controls levels
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PLC patients | Active Comparator | one skin biopsy (lesional) and serum sample will be taken from every patient |
|
| healthy controls | Experimental | a skin biopsy and serum sample will be taken from each control sample |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| skin biopsy and serum sample | Procedure | skin biopsy from lesional skin and serum sample will be taken from each patient . also a skin biopsy and serum sample will be taken from each healthy control |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of tissue and serum levels of interleukin 4 (IL -4) in pityriasis lichenoides chronica (PLC) patients and normal controls. | measurement of tisssue and serum levels of interleukin 4 (IL -4) in pityriasis lichenoides chronica (PLC) patients and comparing them with normal controls to control and verify the hypothesisof involvement of IL-4 in the pathogenesis of PLC | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D017514 | Pityriasis Lichenoides |
| ID | Term |
|---|---|
| D017512 | Lichenoid Eruptions |
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| D010267 | Parapsoriasis |
| D010915 | Pityriasis |