Study of Placental Inflammation in Gestational Diabetes

Study of Placental Inflammation in Gestational Diabetes: the Role of the Inflammosome NLRP3 and the Scavenger Receptor of Inflammatory Chemokines D6

The aim of this study is to investigate the placental inflammation in women with gestational diabetes mellitus, in particular the role of inflammasome NLRP3 and the chemokine scavenger decoy receptor D6

The aim of this study is to investigate systemic and placental inflammation in women with gestational diabetes mellitus, in particular the role of inflammasome NLRP3 and the chemokine scavenger decoy receptor D6, compared to women with uncomplicated pregnancy

Inclusion Criteria:

• Women with gestational diabetes mellitus
• Women with uncomplicated pregnancy
• Age >18 years
• Singleton pregnancy

Exclusion Criteria:

• Age < 18 years
• Infections (HIV,HCV)
• Multiple pregnancy
• Cancer