Relationship Between Gestational Diabetes Mellitus and Inflammatory Adipocytokins in Obese Mothers and Their Newborn at Delivery

Relation Entre diabète Gestationnel et Adipocytokines Inflammatoires Chez Des mères obèses et Leur Nouveau-né à l'Accouchement

ADIPOGEST study aims at comparing circulating levels of inflammatory adipocytokins and C-reactive protein in obese women and their newborn at delivery whether exposed or not to Gestational Diabetes Mellitus (GDM)

ADIPOGEST is a cross sectional study in which mothers are divided into 2 groups : exposed and unexposed to GDM, matched on pregestational BMI, date of delivery and child gender.

Mothers are recruited in the maternity ward of the University Hospital in South of Reunion Island.

It is planned a conveniance sample of 20 mother-child pairs per group.

Inclusion Criteria:

• Pregnant women
• Obese women (BMI : 30 kg/m² or more)
• Aged over 18 years
• With single pregnancy
• With alive newborn at 37 weeks of amenorrhea or more
• With informed consent

Exclusion Criteria:

• Smoker
• Treatments by corticoïds or thyroid hormons
• Overt diabetes
• Complicated pregnancy
• Premature delivery threat