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This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal
In this prospective, randomized controlled trial,130 patients who underwent mandibular third molar surgical removal were divided into two groups: one group used chlorhexidine for postoperative rinsing and the other did not rinse. Pain levels, measured using the Numeric Rating Scale (NRS), were recorded daily for the first seven days post-surgery. Paired-samples t-tests were utilized for data analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Post-operative rinsing with chlorhexidine | Other | In the rinsing group, the patients received a bottle of 0,2% chlorhexidine |
|
| No post-operative rinsing | No Intervention | Those allocated to the control group received no post-operative rinsing |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chlorhexidine Digluconate Mouthwash without Alcohol | Other | In the rinsing group, the patients received a bottle of 0,2% chlorhexidine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative pain after removal of third molar | The primary endpoint is the difference in the postoperative pain measured on a numerical rating scale (NRS) evaluated at seven days | 7 days after the inclusion pain was measured on a numerical rating scale |
| Measure | Description | Time Frame |
|---|---|---|
| Post-operative complications | As secondary outcome measures alveolitis, foodimpaction, bleeding or infection | 7 days after the treatment the patient was seen at the outpatient clinic for clinical assessment. At this moment the number of patients with alveolitis, foodimpaction and bleeding was scored. |
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Inclusion Criteria:
• healthy adults (18+) referred by their dentist for third molar removal
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Isala Hospital | Zwolle | Overijssel | 8025AB | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26922634 | Background | Ghaeminia H, Hoppenreijs TJ, Xi T, Fennis JP, Maal TJ, Berge SJ, Meijer GJ. Postoperative socket irrigation with drinking tap water reduces the risk of inflammatory complications following surgical removal of third molars: a multicenter randomized trial. Clin Oral Investig. 2017 Jan;21(1):71-83. doi: 10.1007/s00784-016-1751-1. Epub 2016 Feb 27. |
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| ID | Term |
|---|---|
| D000431 | Ethanol |
| ID | Term |
|---|---|
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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