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This observational study aims to evaluate the outcomes of patients with early-stage epithelial ovarian cancer who are treated with minimally invasive surgery (such as laparoscopic or robotic surgery). Specifically, the study will look at:
Post-Surgery Complications
Cancer Outcomes
Researchers will compare two groups of patients:
Group 1: Patients with early-stage ovarian cancer treated with minimally invasive surgery.
Group 2: Patients with early-stage ovarian cancer treated with open surgery. The goal is to see if there are any differences in post-surgery complications, recovery, and cancer outcomes between the two groups.
Fertility-Sparing Treatment:
The study will also compare patients who are undergoing fertility-sparing treatments for early-stage ovarian cancer. Two subgroups will be looked at:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients treated with minimally invasive approach | |||
| Patients treated with open surgery |
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| Measure | Description | Time Frame |
|---|---|---|
| To assess the number of patients with 30-day post-operative complication in the two groups (minimally invasive surgery and open surgery) | From surgery to post-operative day 30 | |
| To assess the number of patients with 30-day post-operative hospital readmission in the two groups (minimally invasive surgery and open surgery) | From surgery to post-operative day 30 | |
| To assess the number of patients with 30-day post-operative reoperation in the two groups (minimally invasive surgery and open surgery) | From surgery to post-operative day 30 | |
| To assess the rate of upstaging in the two groups (minimally invasive surgery and open surgery) | At the time of surgery | |
| To assess the rate of conversion in the minimally invasive surgery group | At the time of surgery |
| Measure | Description | Time Frame |
|---|---|---|
| To analyze predictor of recurrence and oncological outcomes in terms of disease-free survival (DFS) and overall survival (OS) in the minimally invasive surgery and in the open surgery groups | From the date of surgery to the date of the last follow-up or the date of recurrence/death, whichever occurs first, assessed up to 300 weeks |
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Inclusion Criteria:
Exclusion Criteria:
patients eligible need to have apparent early stage epithelial ovarian cancer, therefore they need to have a female reproductive system
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The current study is a retrospective multicentric international observational study of data from patients with apparent early-stage epithelial ovarian cancer who underwent minimally-invasive or open surgery between January 2014 and December 2023.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jvan Casarin, Medical Doctor | Contact | +39 3335384990 | j.casarin@uninsubria.it | |
| Anna Giudici, Medical Doctor | Contact | +39 3317099194 |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ospedale Filippo del Ponte | Recruiting | Varese | Varese | 21100 | Italy |
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| ID | Term |
|---|---|
| D000077216 | Carcinoma, Ovarian Epithelial |
| ID | Term |
|---|---|
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| D010051 |
| Ovarian Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
| D009371 | Neoplasms by Site |
| D010049 | Ovarian Diseases |
| D000291 | Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D005833 | Genital Neoplasms, Female |
| D014565 | Urogenital Neoplasms |
| D000091662 | Genital Diseases |
| D004700 | Endocrine System Diseases |
| D006058 | Gonadal Disorders |