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| ID | Type | Description | Link |
|---|---|---|---|
| 2K24HL144917 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | NIH |
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The goal of this study is to 1) use magnetic resonance imaging (MRI) to evaluate the effect of nutritious foods on inflammation in the human hypothalamus of children and 2) assess the feasibility and acceptability of nutritious food feeding intervention strategies in children with overweight or obesity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Focus Group and Child Taste Test (Study 1) | No Intervention | No intervention is administered. Adult caregivers will participate in a focus group to assess feasibility of a controlled feeding study in children and children will complete a taste-test of a controlled feeding study menu. | |
| Study-provided food (Study 2) | Experimental | Participants will be provided all meals for a 7-day period. For the other 7-days of their enrollment, they will be asked to consume their usual diet. |
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| Focus Group (Study 3) | No Intervention | No intervention is administered. Adult caregivers of children will participate in a focus group to learn from families about participating in research involving feeding studies in children. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Diet modification | Other | In Study 2 only, children will be provided all meals for a 7-day period. Meals will consist of nutritious foods, calories provided will exceed the child's estimated daily caloric need, and children will be asked to consume meals ad libitum. |
| Measure | Description | Time Frame |
|---|---|---|
| T2 relaxation time by brain MRI | 7 days of diet intervention |
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Inclusion Criteria:
Exclusion Criteria (study 1 child participants and study 3 criteria for children of adult participants):
Exclusion Criteria (study 2, child participants):
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| BRIDGE Study | Contact | 206 616-6360 | bridge-study@uw.edu |
| Name | Affiliation | Role |
|---|---|---|
| Ellen Schur, MD | University of Washington | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Washington | Recruiting | Seattle | Washington | 98109 | United States |
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| ID | Term |
|---|---|
| D005911 | Gliosis |
| D063766 | Pediatric Obesity |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009765 | Obesity |
| D050177 | Overweight |
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| ID | Term |
|---|---|
| D004035 | Diet Therapy |
| ID | Term |
|---|---|
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
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| D044343 |
| Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |