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The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity. It will also learn about the safety of using fluoride iontophoresis with Acidulated phosphate fluoride gel.
The main questions it aims to answer are:
Does the remineralizing agent have the ability to decrease dentin sensitivity?
Researchers will compare Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel , Casein phosphopeptides-Amorphus calcium phosphate (CPP-ACP), nano-hydroxyapptite (NHAP) and -active glass in decreasing dentin hypersensitivity
.
Participants will:
Assess the efficacy of fluoride iontophoresis in remineralization in comparison with other ingredients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel | Experimental | assessmen of iontophoresis effect on flouride ions flush to remineralization of demineralized enamel .The treatment will be assessed and recorded using VAS score immediately after the intervention, 3 months, 6 months and one year later. |
|
| remineralizing agents | Active Comparator | All remineralizing agents (Casein phosphopeptides -Amorphus Calcium Phosphate, Nano-hydroxyapatite, and Bioactive glass). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fluoride Iontophoresis with Acidulated Phosphate Fluoride | Drug | Application of fluoride gel and activated with Iontophoresis electrical pole |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analogue Scale | Measurement of sensitivity was performed after each stimulus by a Visual Analogue Scale, which consists of a 10-cm long line; the minimum value is 0 and the maximum value is 10, whether the higher scores mean worse and the lower score means better outcome. The patient's pain limits can suffer through an external stimulus; at 0, one end represents absence of discomfort, and the other represents severe discomfort caused by certain stimuli. Each time the patient is subjected to a stimulus, he or she is requested to point at the interval from 0 to 10, a number to correspond to the pain felt. The convenience of this type of scale is to allow demonstration of the pain intensity with absolute numbers or as a percentage of a maximum value | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mohamed Wakwak, A | Alazhar Univeristy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dental Medicine ,Alazhar Univerisity | Cairo | Cairo Governorate | 11768 | Egypt |
privacy of patient may be may be photo of device used in the study , photo of treatment
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| ID | Term |
|---|---|
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D000149 | Acidulated Phosphate Fluoride |
| ID | Term |
|---|---|
| D010710 | Phosphates |
| D010756 | Phosphoric Acids |
| D017976 | Phosphorus Acids |
| D000148 | Acids, Noncarboxylic |
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| Remineralization with sodium fluoride varnish | Drug | CASIN PHOSPHOPEPTIDE AMORPHOUS CALCIUM PHOSPHATE |
|
| D000143 |
| Acids |
| D007287 | Inorganic Chemicals |
| D012969 | Sodium Fluoride |
| D005459 | Fluorides |
| D006858 | Hydrofluoric Acid |
| D017611 | Fluorine Compounds |
| D017553 | Phosphorus Compounds |
| D017670 | Sodium Compounds |
| D002327 | Cariostatic Agents |
| D001697 | Biomedical and Dental Materials |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |