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Aim of the study will be conducted to compare the efficacy of bifluoride (NaF and CaF) versus conventional fluoride varnish (Sodium Flouride) in the management of hypersensitivity of exposed cervical area in adult patients over 2 month
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| bifluorid 10 varnish | Experimental | Bifluorid 10 (NaF and CaF) lead to reduce the dentin hypersensitivity, the sodium fluoride (NaF) dissociates and releases F ions, that diffuse through the tubules and then precipitates as calcium fluoride as a consequence of the high of calcium content in saliva and dentinal fluid ,The calcium fluoride (CaF) present in the varnish composition diffuses into the tubules and block the canal with a semi-permanent protective layer.The calcium fluoride is added to block the dentin tubules mechanically, by the combination with the calcium fluoride resulted from the sodium fluoride reaction to the calcium of dentin. |
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| sodium fluoride varnish | Active Comparator | Topical application of varnish fluoride (sodium fluoride NaF) effect on exposed dentine as a desensitizing agent, the varnish fluoride process is caused by the reaction between NaF and calcium ions resulting in calcium fluoride crystals being deposited on the openings of the dentinal tubules that decrease pain. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bifluorid 10 ,VOCO | Drug | NaF and CaF 10 % |
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| Measure | Description | Time Frame |
|---|---|---|
| Dentin hypersensitivity | measurement of dentin hypersensitivity by VAS scale | pre-intervention |
| Dentin hypersensitivity | measurement of dentin hypersensitivity by VAS scale | 2 min |
| Dentin hypersensitivity | measurement of dentin hypersensitivity by VAS scale | 1 week |
| Dentin hypersensitivity | measurement of dentin hypersensitivity by VAS scale | 4 weeks |
| Dentin hypersensitivity | measurement of dentin hypersensitivity by VAS scale | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Dentinal tubule occlusion | Percentage of dentinal tubule occlusion measure by scanning electron microscope SEM | Pre-intervention |
| Dentinal tubule occlusion | Percentage of dentinal tubule occlusion measure by scanning electron microscope SEM |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zaid Yousef Alkhatteb, BSc | Contact | 00201272111897 | zaid_yousef@denstistry.cu.edu.eg |
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| ID | Term |
|---|---|
| D006967 | Hypersensitivity |
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D007154 | Immune System Diseases |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D012969 | Sodium Fluoride |
| ID | Term |
|---|---|
| D005459 | Fluorides |
| D006858 | Hydrofluoric Acid |
| D017611 | Fluorine Compounds |
| D007287 | Inorganic Chemicals |
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| Sodium Fluoride 5% Dental Varnish | Drug | 5% NaF |
|
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| 8 weeks |
| D017670 |
| Sodium Compounds |
| D002327 | Cariostatic Agents |
| D001697 | Biomedical and Dental Materials |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |