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2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.
In-vivo part:
Each varnish will be applied separately on different teeth according to the manufacturer's instructions and the VAS will be measured according to a specific timeline: T0 (baseline, before application of varnish), T1 (1 week after application), T2 (4 weeks after application) and T3 (4 weeks after application).
In-situ part:
Dentin specimen will be prepared from extracted teeth from the orthodontic department in our college, sterilized and prepared.
it will be bonded to an orthodontic wire and bonded to upper first molar. Dentinal occlusion will be measured using scanning electron microscope following the same timeline.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Citrine 5% Sodium Fluoride | Active Comparator | It was developed to prolong the contact between the tooth surface and fluoride to increase the resistance against caries attack and manage tooth hypersensitivity; the active ingredient of fluoride varnish is mostly 5% sodium fluoride. |
|
| concocuted Nano-silver fluoride | Experimental | Nano-silver fluoride (NSF) is a laboratory synthesized solution |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Citrine 5 % sodium fluoride | Behavioral | Citrine varnish is a 5% sodium fluoride varnish, It was developed to prolong the contact between the tooth surface and fluoride to increase the resistance against caries attack and manage tooth hypersensitivity; the active ingredient of fluoride varnish is mostly 5% sodium fluoride. |
| Measure | Description | Time Frame |
|---|---|---|
| change in dentin Hypersensitivity | Visual Analogue Scale (VAS) will be used; 0 is no pain and 10 is severe pain. Pictures are added to the same, as well as colors to guide the patient during selection of pain severity. | 1 week, 4 weeks & 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| change in dentinal Tubule Occlusion | the dentinal tubule occlusion of citrine 5% sodium fluoride and the dentinal tubule occlusion of nano-silver fluoride for treatment of dentin hypersensitivity and compare them together | 1 week, 4 weeks * 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
• Patients participating in another dental study that may alter the results of this study.
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| ID | Term |
|---|---|
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D012969 | Sodium Fluoride |
| ID | Term |
|---|---|
| D005459 | Fluorides |
| D006858 | Hydrofluoric Acid |
| D017611 | Fluorine Compounds |
| D007287 | Inorganic Chemicals |
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|
| concocted nano-silver fluoride | Behavioral | Nano-silver fluoride (NSF) is a solution which has been introduced as an experimental formulation in which it's stability for three years has been proved by Santos et al. The laboratory synthesis of concocted NSF was carried out in a nano-technology center; Several trials were done until we have reached a successful end product. |
|
| D017670 |
| Sodium Compounds |
| D002327 | Cariostatic Agents |
| D001697 | Biomedical and Dental Materials |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |