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Women generally live longer than men but often experience a faster muscle mass loss due to inactivity, which can lead to weakness and disability. Despite these risks, women, particularly older women, are less active than men. In England, less than one-third of women engage in sufficient aerobic activity, and less than 5% do enough muscle strength training. Common reasons for not exercising include lack of time and enjoyment.
High-intensity interval training (HIIT) is an efficient and effective way to exercise that many women find more enjoyable than longer workouts. HIIT has been shown to be effective in older women, helping them improve their fitness with less time commitment. Because HIIT is time-efficient, it can be combined with muscle strength training without significantly increasing the duration of the exercise session, which may lead to even better fitness results.
This study will assess how practical it is for older women to do HIIT and strength exercise combined training. It will also investigate whether this combined approach can improve overall fitness, muscle strength, aerobic fitness, and quality of life more than HIIT alone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| aerobic training + muscle strength training | Experimental | 3 days/week -- 3-min warm up at 60% of HR@VT2 on a bike ergometer -- 6 x 1-min machine-base muscle strength exercises: leg press, chest press, knee extension, lat pull down, knee flexion, and shoulder raise -- 6 x 1-min high-intensity interval bouts at 80% HR@VT2 interspersed by 1-min active recovery will be performed. |
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| aerobic training | Active Comparator | 3 days/week -- 3-min warm up at 60% of HR@VT2 on a bike ergometer -- 2 blocks of 6 x 1-min high-intensity interval bouts at 70% HR@VT2 interspersed by 1-min active recovery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Behavioral | Participants will attend 30-min training sessions 3 times a week for 12 weeks. The intensity of HIIT will be at 80% HR@VT2 measured in the first week and will increase to 90% in the second week. By week 3, the intensity will reach HR@VT2. |
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility of high-intensity interval training combined with muscle strength training | will be assessed from recruitment, adherence, compliance, safety, subjective exercise experiences and self-efficacy. Recruitment will be assessed by the proportion of patients remained interested and randomized after being informed of the requirements of the study; adherence will be assessed by the attendance to the prescribed exercise sessions; and compliance will be assessed by the proportion of participants adhering to prescribed exercise intensity. For safety, all mild, moderate, and severe symptoms and adverse events throughout this study will be recorded. | From recruitment to week-12 |
| Measure | Description | Time Frame |
|---|---|---|
| functional capacity | will be assessed using the Fullerton Functional Fitness Test, a valid and reliable measure of functional independence in older adults | From baseline to week-12 |
| muscle function |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tasuku Terada, PhD | Contact | 441158230141 | tasuku.terada@nottingham.ac.uk |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| David Greenfield Humnn Physiology Unit (DGHPU), University of Nottingham | Recruiting | Nottingham | Nottingham | NG72UH | United Kingdom |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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Isometric strength, isokinetic muscle torque (i.e., strength) and fatigue will be measured using a dynamometer (CYBEX).
| From baseline to week-12 |
| cardiorespiratory fitness | will be measured by a gold-standard, symptom-limited CPET using metabolic equipment on an electronically braked cycle ergometer. | From baseline to week-12 |
| muscle mass | will be measured using ultrasound at the mind-point of the thigh, from the greater trochanter to mid patella. | From baseline to week-12 |
| QoL | will be assessed using Short Form 36 Health Survey Questionnaire (SF-36). | From baseline to week-12 |