The Methylation Level of the Orexin Gene in Anorexia Nervosa: Relationship With Eating Disorder, Depressive State, and Sleep Quality
The Methylation Level of the Orexin Gene in Anorexia Nervosa: Relationship With Eating Disorder, Depressive State, and Sleep Quality
The objectives of this study will be to determine the methylation of the promoter of the Orexin A (OX-A) and B (OX-B) genes in young women (> 18 years) with Anorexia Nervosa (AN), compared with a control group; and to evaluate the relationship of promoter methylation of the genes for OX-A and OX-B with the severity of the eating disorder, psychiatric comorbidities (in particular, depression), and sleep quality.
Patients with Anorexia Nervosa:
Inclusion Criteria:
Exclusion Criteria:
Control group:
Inclusion Criteria:
Exclusion Criteria:
sartorio@auxologico.it+390261911 ext. 2426
luca.grappiolo@auxologico.it+390261911 ext. 2894