Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese, and trained young athletes. The main questions it aims to answer are:
Can EI reliably and accurately measure muscle quality in children when validated against gold-standard techniques like DXA and isokinetic dynamometry? What are the age-, sex-, and fitness-specific benchmarks for EI to differentiate between normal and pathological muscle quality?
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Echo intensity of the vastus lateralis (VL) and rectus femoris (RF) muscles | Echo intensity will be measured by greyscale analysis derivered from ultrasound imaging. | Through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Skeletal Muscle Mass | Measured using DXA (Horizon DXA platform, Hologic) | Through study completion, an average of 1 year |
| Muscle Strength | Assessed via isokinetic and isometric knee extensor strength using a Humac Norm isokinetic dynamometer |
Not provided
Inclusion Criteria:
• Generally healthy children
Exclusion Criteria:
Not provided
Not provided
Sixty boys and sixty girls aged 10-14 years, evenly distributed as follows: normal-weight children, trained young athletes (≥3 training sessions per week), and obese children according to BMI
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Michal Steffl, PhD | Contact | +420778701882 | michal.steffl@ftvs.cuni.cz |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Physical Education and Sport Charles University | Prague | Czech Republic | 16200 | Czechia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41005786 | Derived | Jandova T, Kinkorova I, Vetrovsky T, Mala J, Musilova E, Steffl M, Narici MV. Can ultrasound echo intensity assess muscle quality in children aged 10-14 years? Protocol for a cross-sectional validation study in Czech children. BMJ Open. 2025 Sep 26;15(9):e100495. doi: 10.1136/bmjopen-2025-100495. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Through study completion, an average of 1 year |