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To assess the outcome of posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients in Assuit university hospitals and El Rajhi hospital.
Cholelithiasis is found in about one third of patients with liver cirrhosis and about twice as much as in the overall population. Predisposing factors for that include functional gallbladder alterations (reduced motility and decreased emptying), reduction in bile acidity, increased unconjugated bilirubin secretion, increased levels of estrogen, and increased intravascular haemolysis due to hypersplenism. Symptomatic biliary stones in patients with liver cirrhosis are associated with higher morbidity and mortality rates than those in patients with a non-cirrhotic liver. laparoscopic cholecystectomy is the gold standard for the treatment of most of gallbladder problems because of its several advantages over open cholecystectomy including shorter convalescence period and hospital stay. Furthermore, considering its safety, it is the gold-standard procedure in selected patients with symptomatic cholelithiasis and hepatic cirrhosis, especially Child-Pugh score A and B patients. Separation of posterior wall of the gallbladder from the liver bed in cirrhotic individuals is difficult and risky during a laparoscopic cholecystectomy surgery because of high-risk gall bladder bed due to fibrosis and tortuous, dilated vessels there so the strategy is leaving the posterior wall intact with the liver and the remnant mucosa was removed either by mucosectomy in patients with acute cholecystitis or by electro fulguration in those with chronic cholecystitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients | To assess the outcome of posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patient |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| laparoscopic cholecystectomy | Procedure | Posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intra and Post-operative haemorrhage | Surgery then 2 days follow up | |
| Postoperative bile leak | Surgery then 1 week follow up | |
| Changes of liver function tests | AST, ALT, Billirubin | Surgery then 1 week follow up |
| Worsening of ascites | Surgery then 1 week follow up | |
| Port site infection | Surgery then 1 week folow up |
| Measure | Description | Time Frame |
|---|---|---|
| Operative time | From the end of induction of anasthesia to the closure of port site incisions | |
| Postoperative hospital stay | surgery then up to 1 week hospital stay before discharge |
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Inclusion Criteria:
Exclusion Criteria:
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60 cirrhotic patients age from 18 to 60 years who were admitted for cholecystectomy
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Adnan mohamed Mohamed Mohamed salem | Contact | 01111846484 | Adnan.16281240@med.aun.edu.eg | |
| Mostafa Mahmoud Mohamed Ibrahim, Lecturer | Contact | 01095295794 | mostafamahmoud562@au.edu.eg |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20202403 | Result | Shaikh AR, Muneer A. Laparoscopic cholecystectomy in cirrhotic patients. JSLS. 2009 Oct-Dec;13(4):592-6. doi: 10.4293/108680809X12589999537959. | |
| 16021366 | Result | Schiff J, Misra M, Rendon G, Rothschild J, Schwaitzberg S. Laparoscopic cholecystectomy in cirrhotic patients. Surg Endosc. 2005 Sep;19(9):1278-81. doi: 10.1007/s00464-004-8823-z. Epub 2005 Jul 21. |
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| ID | Term |
|---|---|
| D017081 | Cholecystectomy, Laparoscopic |
| ID | Term |
|---|---|
| D002763 | Cholecystectomy |
| D001662 | Biliary Tract Surgical Procedures |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| 16864026 | Result | Palanivelu C, Rajan PS, Jani K, Shetty AR, Sendhilkumar K, Senthilnathan P, Parthasarthi R. Laparoscopic cholecystectomy in cirrhotic patients: the role of subtotal cholecystectomy and its variants. J Am Coll Surg. 2006 Aug;203(2):145-51. doi: 10.1016/j.jamcollsurg.2006.04.019. Epub 2006 Jun 22. |
| 32369724 | Result | Cassinotti E, Baldari L, Boni L, Uranues S, Fingerhut A. Laparoscopic Cholecystectomy in the Cirrhotic: Review of Literature on Indications and Technique. Chirurgia (Bucur). 2020 Mar-Apr;115(2):208-212. doi: 10.21614/chirurgia.115.2.208. |
| D010535 | Laparoscopy |
| D004724 | Endoscopy |
| D019060 | Minimally Invasive Surgical Procedures |