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| Name | Class |
|---|---|
| The First Affiliated Hospital of Henan University of Traditional Chinese Medicine | OTHER |
| Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine | OTHER |
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For patients with poor asthma control, on the basis of treatment guided by GINA guidelines, lung-benefiting moxibustion treatment will be given, and it will be applied 10 days before "early onset", once every 10 days, and the follow-up was 45 weeks, 1 cycle per year, for 2 consecutive cycles (2 years). The annual number of flare-up of asthma patients will be used as the main outcome index to evaluate the clinical effect of lung-benefiting moxibustion on reducing exacerbations of asthma. By observing immunoglobulin, T cell subsets and other indicators, the advantage population and mechanism of moxibustion in treating patients with poor asthma control will be clarified.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| test group | Experimental | On the basis of the control group, lung-benefiting moxibustion treatment will be given.Details are as follows:
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| control group | Active Comparator | Refer to "GINA (2024)". Regulations on combined medication: When complications occur during treatment, symptomatic treatment can be given according to the clinical situation. At the same time, the name, manufacturer, batch number, usage, dosage, course of treatment, etc. of the drug should be recorded in detail. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| lung-benefiting moxibustion | Other | A kind of external treatment,the treatment theory is to treat winter diseases in summer. |
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| Measure | Description | Time Frame |
|---|---|---|
| Annual number of flare-up of asthma | Frequency | 1year |
| Measure | Description | Time Frame |
|---|---|---|
| ACT and ACQ questionnaires |
| Before treatment, and at 7, 13, 26, 39, 52, 59, 65, 78, 91, and 104 weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| C Feng | Contact | 010-88325882 | fengcuiling@sina.com |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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| The specific drug comes from "GINA (2024)" | Drug | Refer to "GINA (2024)". |
|
| AQLQ scale | Asthma Quality of Life Questionnaire When calculating the overall score, the scores of each dimension are averaged to obtain a score between 0 and 7. The higher the score, worse the patient's quality of life. According to the AQLQ scoring criteria, a score above 5 indicates a relatively good quality of life, while a below 3 indicates a poor quality of life. | Before treatment, and at 7, 13, 26, 39, 52, 59, 65, 78, 91, 104 weeks. |
| Pulmonary ventilation test and Diastolic test | Ventilation function test ml | Pulmonary ventilation test will be performed once before treatment,and at 52, 104 weeks.Diastolic tests will be performed once before treatment. |
| FeNO | The fractional concentration of exhaled nitric oxide | Before treatment,and at 52, 104 weeks. |
| Eosinophils count,Serum total IgE,and T-Lymphocyte Subsets | EO# x 10^9/L Ig E IU/mL percent of CD4+ cell、CD8+ cell 、CD4+/CD8+ cell | Before treatment,and at 7, 52, 59, 104 weeks. |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |