Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial

Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial

The purpose of this study is to develop an evidence-based precision medicine approach for obesity that enhances weight loss and promotes weight loss maintenance.

Inclusion:

• men or women between 18 to 65 years with obesity (BMI>30kg/m2).

Exclusion:

• weight change greater than 3% in the previous 3 months
• history of bariatric surgery and bariatric endoscopy
• untreated psychiatric disorders including binge eating disorders and bulimia
• current use of AOMs
• history of use of medications affecting weight or energy intake or energy expenditure in the last 6 months
• history of type 1 diabetes mellitus or uncontrolled medical conditions (e.g., uncontrolled hypertension)
• women who are pregnant or plan to become pregnant,
• any condition that limits their participation in the study
• Principal Investigator discretion