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| Name | Class |
|---|---|
| Danone Global Research & Innovation Center | INDUSTRY |
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The study included 21 adult participants, aged 19-46 years (19 female participants and 2 male participants). The selection criteria included the following parameters: Body Mass Index (BMI), calculated as weight (kg) divided by height squared (m²), between 18.5 and 29.99; Waist-to-Hip Ratio with thresholds set at >0.90 for males and >0.85 for females for individuals with normal weight (eutrophic); percentage of body fat: Considered within normal range if <30% for individuals with normal weight. Standard biochemical and anthropometric measurements were carried out to all the subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | Healthy subjects |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lactobacillus casei DN-114001 | Dietary Supplement | Probiotic |
|
| Measure | Description | Time Frame |
|---|---|---|
| Fecal flora cultures (Count of colonies/mL) | Relative amount of colonies (CFU) of Escherichia coli, Clostridium species and Lactobacillus | From enrollment to the end of treatment at 45 days weeks, every 15 days |
| Serum immunoglobulins | Serum concentration of G, A, M, and G subclasses, as well as the complement C3 and C4 factors, | From enrollment to the end of treatment at 45 days weeks, every 15 days |
| Lymphocyte Subpopulations | Concentration of T Lymphocytes: CD3, CD4, CD8, CD45 RA, and CD45 RO (distinguishing between helper T cells, cytotoxic T cells, and naïve or memory subsets within each group). ii) B Lymphocytes: CD19; iii) NK Cells: CD16 and CD56. | From enrollment to the end of treatment at 45 days weeks, every 15 days |
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Inclusion Criteria:
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Sequential intervention
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