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| Name | Class |
|---|---|
| University Grenoble Alps | OTHER |
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Acquisition of synchronized cardiovascular signals from non-invasive measurements (ECG, photoplethysmography pulse sensors, inductance plethysmography) in healthy volunteers aged from 18 to 75, during spontaneous ventilation with apneas (20 seconds) for a total acquisition time of 30 minutes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Under 30 | Healthy volunteers younger than 30 years |
| |
| Between 30 and 50 | Healthy volunteers between 30 and 50 years |
| |
| More than 50 | Healthy volunteers older than 50 years |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| physiological signal acquisitions | Other | Subjects will be fitted with non-intrusive devices. In a semi-recumbent position, they will be asked to perform
This single participation session will last a total of one hour for the volunteer (equipment, recording, de-equipping), including 30 minutes of acquisition. |
| Measure | Description | Time Frame |
|---|---|---|
| Electrocardiogram | acquisition of ECG signals | 1 hour |
| Photoplethysmography | acquisition of peripheral and central photoplethysmographic signals with radial, brachial, carotid and femoral sensors | 1 hour |
| inductive plethysmography | acquisition of abdominal and thoracic section variations with an inductive plethysmographic vest | 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| link between peripheral and central pulse wave velocity | Assesment of the link between peripheral and central vascular function with statistical analysis (Linear regression, Bland and Altman test) | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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60 healthy volunteers: 3 groups of 20 volunteers per age category (under 30, between 30 and 50, over 50)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stéphane TANGUY | Contact | +33476637117 | stephane.tanguy@univ-grenoble-alpes.fr |
| Name | Affiliation | Role |
|---|---|---|
| Stéphane TANGUY | University Grenoble Alpes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratoire TIMC | Grenoble | 38000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25215227 | Background | Diaz A, Galli C, Tringler M, Ramirez A, Cabrera Fischer EI. Reference values of pulse wave velocity in healthy people from an urban and rural argentinean population. Int J Hypertens. 2014;2014:653239. doi: 10.1155/2014/653239. Epub 2014 Aug 24. | |
| 33018566 | Background | Fontecave-Jallon J, Tanguy S. Inductive Plethysmography for aortic Pulse Wave Velocity. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2711-2714. doi: 10.1109/EMBC44109.2020.9175329. |
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| 27195235 | Background | Fortier C, Agharazii M. Arterial Stiffness Gradient. Pulse (Basel). 2016 Apr;3(3-4):159-66. doi: 10.1159/000438852. Epub 2015 Sep 2. |
| 27821616 | Background | Fortier C, Sidibe A, Desjardins MP, Marquis K, De Serres SA, Mac-Way F, Agharazii M. Aortic-Brachial Pulse Wave Velocity Ratio: A Blood Pressure-Independent Index of Vascular Aging. Hypertension. 2017 Jan;69(1):96-101. doi: 10.1161/HYPERTENSIONAHA.116.08409. Epub 2016 Nov 7. |
| 36701358 | Background | Heffernan KS, Stoner L, London AS, Augustine JA, Lefferts WK. Estimated pulse wave velocity as a measure of vascular aging. PLoS One. 2023 Jan 26;18(1):e0280896. doi: 10.1371/journal.pone.0280896. eCollection 2023. |
| 32188277 | Background | Yu S, McEniery CM. Central Versus Peripheral Artery Stiffening and Cardiovascular Risk. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1028-1033. doi: 10.1161/ATVBAHA.120.313128. Epub 2020 Mar 19. |
| 25668350 | Background | Weber T, Wassertheurer S, Hametner B, Parragh S, Eber B. Noninvasive methods to assess pulse wave velocity: comparison with the invasive gold standard and relationship with organ damage. J Hypertens. 2015 May;33(5):1023-31. doi: 10.1097/HJH.0000000000000518. |
| 37963909 | Background | Wang J, Jing C, Hu X, Cui J, Tang Q, Tu L, Zhao S, Huang J, Guo D, Li Y, Xu J. Assessment of aortic to peripheral vascular stiffness and gradient by segmented upper limb PWV in healthy and hypertensive individuals. Sci Rep. 2023 Nov 13;13(1):19859. doi: 10.1038/s41598-023-46932-0. |
| 26160955 | Background | Townsend RR, Wilkinson IB, Schiffrin EL, Avolio AP, Chirinos JA, Cockcroft JR, Heffernan KS, Lakatta EG, McEniery CM, Mitchell GF, Najjar SS, Nichols WW, Urbina EM, Weber T; American Heart Association Council on Hypertension. Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness: A Scientific Statement From the American Heart Association. Hypertension. 2015 Sep;66(3):698-722. doi: 10.1161/HYP.0000000000000033. Epub 2015 Jul 9. No abstract available. |
| 23681924 | Background | Sztrymf B, Jacobs F, Chemla D, Richard C, Millasseau SC. Validation of the new Complior sensor to record pressure signals non-invasively. J Clin Monit Comput. 2013 Dec;27(6):613-9. doi: 10.1007/s10877-013-9477-y. Epub 2013 May 17. |
| 35456316 | Background | Salvi P, Valbusa F, Kearney-Schwartz A, Labat C, Grillo A, Parati G, Benetos A. Non-Invasive Assessment of Arterial Stiffness: Pulse Wave Velocity, Pulse Wave Analysis and Carotid Cross-Sectional Distensibility: Comparison between Methods. J Clin Med. 2022 Apr 15;11(8):2225. doi: 10.3390/jcm11082225. |
| 15614022 | Background | Salvi P, Lio G, Labat C, Ricci E, Pannier B, Benetos A. Validation of a new non-invasive portable tonometer for determining arterial pressure wave and pulse wave velocity: the PulsePen device. J Hypertens. 2004 Dec;22(12):2285-93. doi: 10.1097/00004872-200412000-00010. |
| 28379892 | Background | Obeid H, Khettab H, Marais L, Hallab M, Laurent S, Boutouyrie P. Evaluation of arterial stiffness by finger-toe pulse wave velocity: optimization of signal processing and clinical validation. J Hypertens. 2017 Aug;35(8):1618-1625. doi: 10.1097/HJH.0000000000001371. |
| 38139728 | Background | Karimpour P, May JM, Kyriacou PA. Photoplethysmography for the Assessment of Arterial Stiffness. Sensors (Basel). 2023 Dec 17;23(24):9882. doi: 10.3390/s23249882. |