Postoperative Pain in Endodontic Therapy

The Effect of Different Irrigation Activation Methods Preferred During Root Canal Treatment On Postoperative Pain: A Randomized Clinical Trial

The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation methods.

The null hypothesis is: "There is no difference in postoperative pain after root canal treatment between the irrigation activation systems in mandibular first molars and premolar teeth."

Inclusion Criteria:

• Patients aged between 18 and 55 years, medically healthy, and free from systemic diseases.
• Patients without pregnancy or breastfeeding status.
• Patients diagnosed with asymptomatic apical periodontitis confirmed through radiographic and clinical examination.
• Patients not having a regular intake of analgesic or anti-inflammatory drugs within the last 12 hours.
• Patients lacking a history of drug allergies.
• Teeth free from calcifications, resorptions, periodontal problems, incomplete root development, a history of endodontic treatment, traumatic occlusion, or severe coronal destruction.
• Teeth with a root canal curvature of 5° or less.
• Mandibular premolars and first molars.

Exclusion Criteria:

• Teeth where the apical area could not be reached with a #8K file.
• Teeth with an apical diameter larger than #20K file.
• Patients with a Periapical Index (PAI) score of 1 or 2.
• Teeth having extra canals.
• Teeth requiring a second local anesthesia during treatment.
• Teeth where a file fractured within the canal during preparation.
• Vital teeth.
• Patients reporting preoperative pain.
• Teeth showing clinical symptoms such as percussion or palpation sensitivity.
• Teeth with persistent purulent discharge.