A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus... | NCT06717347 | Trialant

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus... | NCT06717347 | Trialant

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Eligibility Criteria: Inclusion Criteria:

Has histologically confirmed diagnosis of diffuse large B-cell lymphoma (DLBCL), by prior biopsy, based on local testing according to the WHO classification of neoplasms of the hematopoietic and lymphoid tissues

Has positron emission tomography (PET) positive disease at screening, defined as 4 to 5 on the Lugano 5-point scale

Has received no prior treatment for their DLBCL

Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2 assessed within 7 days before randomization

Has an ejection fraction ≥45% as determined by either echocardiogram (ECHO) or multigated acquisition (MUGA)

Human immunodeficiency virus (HIV) infected participants must have well controlled HIV on antiretroviral therapy (ART)

Who are hepatitis B surface antigen (HBsAg) positive are eligible if they have received hepatitis B virus (HBV) antiviral therapy and have undetectable HBV viral load prior to randomization

Participants with history of hepatitis C virus (HCV) infection are eligible if HCV viral load is undetectable at screening

Exclusion Criteria:

Has a history of transformation of indolent disease to DLBCL

Has received a diagnosis of primary mediastinal B-cell lymphoma (PMBCL) or Grey zone lymphoma

Has Ann Arbor Stage I DLBCL

Has clinically significant (i.e., active) cardiovascular disease: cerebral vascular accident/stroke (<6 months prior to enrollment), myocardial infarction (<6 months prior to enrollment), unstable angina, congestive heart failure (New York Heart Association Classification Class ≥II), or serious cardiac arrhythmia requiring medication

Has clinically significant pericardial or pleural effusion

Has ongoing Grade >1 peripheral neuropathy

Has a demyelinating form of Charcot-Marie-Tooth disease

HIV-infected participants with a history of Kaposi's sarcoma and/or Multicentric Castleman's Disease

Has ongoing corticosteroid therapy

Has received a live or live-attenuated vaccine within 30 days before the first dose of study intervention. Administration of killed vaccines is allowed

Known additional malignancy that is progressing or has required active treatment within the past 2 years

Known active central nervous system (CNS) lymphoma

Has active autoimmune disease that has required systemic treatment in the past 2 years

Has active infection requiring systemic therapy

Has concurrent active HBV (defined as HBsAg positive and detectable HBV DNA) and HCV (defined as anti-HCV antibody positive and detectable HCV ribonucleic acid (RNA)) infection

Has history of allogeneic tissue/solid organ transplant

USA Mitchell Cancer Institute ( Site 0173)Recruiting

Mobile, Alabama 36604, United States

Study CoordinatorContact

251-445-9875

Banner MD Anderson Cancer Center ( Site 0165)Recruiting

Gilbert, Arizona 85234, United States

Banner MD Anderson Cancer Center - University Medical Center Phoenix ( Site 0167)Recruiting

Phoenix, Arizona 85006, United States

The University of Arizona Cancer Center - North Campus ( Site 0124)Recruiting

Tucson, Arizona 85719, United States

Providence Medical Foundation-Oncology ( Site 0168)Recruiting

Fullerton, California 92835, United States

MemorialCare Health System - Long Beach Medical Center ( Site 9559)Recruiting

Long Beach, California 90806, United States

Cancer Blood and Specialty Clinic ( Site 0109)Recruiting

Los Alamitos, California 90720, United States

Cedars-Sinai Medical Center ( Site 0115)Recruiting

Los Angeles, California 90048, United States

Pacific Hematology Oncology Associates ( Site 0131)Recruiting

San Francisco, California 94115, United States

Lutheran Hospital - Cancer Centers of Colorado ( Site 0180)Recruiting

Golden, Colorado 80401, United States

Clermont Oncology Center ( Site 0182)Recruiting

Clermont, Florida 34711, United States

Bioresearch Partner ( Site 0157)Recruiting

Hialeah, Florida 33013, United States

Orlando Health Cancer Institute ( Site 0169)Recruiting

Ocoee, Florida 34761, United States

Mid Florida Hematology and Oncology Center ( Site 0172)Recruiting

Orange City, Florida 32763, United States

Cancer Care Specialists of Illinois ( Site 0152)Recruiting

O'Fallon, Illinois 62269, United States

Fort Wayne Medical Oncology and Hematology ( Site 0149)Recruiting

Fort Wayne, Indiana 46804, United States

Cotton O'Neil Cancer Center ( Site 0108)Recruiting

Topeka, Kansas 66606, United States

University of Kentucky ( Site 0106)Recruiting

Lexington, Kentucky 40536, United States

Norton Women's and Children's Hospital-Norton Cancer Institute - St. Matthews ( Site 0163)Recruiting

Louisville, Kentucky 40207, United States

Owensboro Medical Health System ( Site 0195)Recruiting

Owensboro, Kentucky 42303, United States

CHRISTUS St. Frances Cabrini Hospital Center for Cancer Care ( Site 0184)Recruiting

Alexandria, Louisiana 71301, United States

American Oncology Partners, P.A. ( Site 0185)Recruiting

Bethesda, Maryland 20817, United States

Karmanos Cancer Institute ( Site 0174)Recruiting

Detroit, Michigan 48201, United States

Corewell Health ( Site 0130)Recruiting

Grand Rapids, Michigan 49503, United States

The University of Mississippi Medical Center ( Site 0161)Recruiting

Jackson, Mississippi 39216, United States

Circuit Clinical - SSM Health Cancer Care DePaul ( Site 0166)Recruiting

Bridgeton, Missouri 63044, United States

Truman Medical Center ( Site 0122)Recruiting

Kansas City, Missouri 64108, United States

Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana ( Site 0178)Recruiting

Billings, Montana 59102, United States

OptumCare Cancer Care ( Site 0121)Recruiting

Las Vegas, Nevada 89102, United States

Comprehensive Cancer Centers of Nevada ( Site 0113)Recruiting

Las Vegas, Nevada 89169, United States

New York Oncology Hematology, P.C. ( Site 0129)Recruiting

Albany, New York 12206, United States

Icahn School of Medicine at Mount Sinai ( Site 0164)Recruiting

New York, New York 10029, United States

East Carolina University ( Site 0159)Recruiting

Greenville, North Carolina 27834, United States

Sanford Health Roger Maris Cancer Center ( Site 0189)Recruiting

Fargo, North Dakota 58102, United States

Kaiser Permanente Interstate Medical Office - Central ( Site 0181)Recruiting

Portland, Oregon 97227, United States

Prisma Health - Upstate ( Site 0158)Recruiting

Greenville, South Carolina 29605, United States

Sanford Cancer Center ( Site 0143)Recruiting

Sioux Falls, South Dakota 57104, United States

The University of Tennessee Medical Center ( Site 0142)Recruiting

Knoxville, Tennessee 37920, United States

Center for Oncology and Blood Disorders ( Site 0153)Completed

Houston, Texas 77030, United States

Houston Methodist Cancer Center ( Site 0154)Recruiting

Houston, Texas 77030, United States

Joe Arrington Cancer Research and Treatment Center ( Site 0183)Recruiting

Lubbock, Texas 79410, United States

University of Virginia Cancer Center ( Site 0138)Recruiting

Charlottesville, Virginia 22903, United States

Virginia Cancer Institute ( Site 0148)Recruiting

Richmond, Virginia 23229, United States

Blue Ridge Cancer Care ( Site 0132)Recruiting

Roanoke, Virginia 24014, United States

Vista Oncology ( Site 4201)Recruiting

Olympia, Washington 98506, United States

SSM Health Dean Medical Group ( Site 0140)Recruiting

Madison, Wisconsin 53715, United States

Clinica Adventista Belgrano ( Site 0309)Recruiting

Caba., Buenos Aires C1430EGF, Argentina

Study CoordinatorContact

+5491140141500

Instituto de Investigaciones Clinicas Mar del Plata ( Site 0306)Recruiting

Mar del Plata, Buenos Aires B7600FZO, Argentina

Hospital Universitario Austral ( Site 0307)Recruiting

Pilar, Buenos Aires B1629AHJ, Argentina

Hospital Aleman ( Site 0301)Recruiting

Buenos Aires, Buenos Aires F.D. C1118AAT, Argentina

Fundacion Estudios Clinicos ( Site 0311)Recruiting

Rosario, Santa Fe Province S2000CEJ, Argentina

C.I.C.E. 9 de Julio ( Site 0305)Completed

San Miguel de Tucumán, Tucumán Province T4000IKO, Argentina

Hospital Italiano de Buenos Aires ( Site 0304)Recruiting

CABA, C1199ABB, Argentina

Study CoordinatorContact

(011) 4959-0550

Clinica EL Castaño ( Site 0312)Completed

San Juan, J5400ARW, Argentina

Townsville University Hospital ( Site 3006)Recruiting

Townsville, Queensland 4814, Australia

Royal Adelaide Hospital ( Site 3001)Recruiting

Adelaide, South Australia 5000, Australia

Grampians Health ( Site 3003)Recruiting

Ballarat, Victoria 3350, Australia

Northern Hospital ( Site 3002)Recruiting

Melbourne, Victoria 3076, Australia

Royal Perth Hospital-Haematology ( Site 3004)Recruiting

Perth, Western Australia 6000, Australia

AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 1102)Recruiting

Mechelen, Antwerpen 2800, Belgium

ASBL CHU Helora - Hôpital de Mons - Site Kennedy ( Site 1103)Recruiting

Mons, Hainaut 7000, Belgium

CEONC ( Site 0412)Recruiting

Cascavel, Paraná 85803-760, Brazil

Hospital Erasto Gaertner ( Site 0401)Recruiting

Curitiba, Paraná 82520-060, Brazil

Liga Norte Riograndense Contra o Cancer ( Site 0407)Recruiting

Natal, Rio Grande do Norte 59062-000, Brazil

CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina ( Site 0403)Recruiting

Florianópolis, Santa Catarina 88020-210, Brazil

Hope ( Site 0413)Recruiting

Ribeirão Preto, São Paulo 14026-610, Brazil

Clinica Advanze ( Site 0411)Recruiting

São Carlos, São Paulo 13561-130, Brazil

F. F. R. M. São Jose do Rio Preto ( Site 0404)Recruiting

SJRP, São Paulo 15090-000, Brazil

Study CoordinatorContact

+55 17 99788 6883

Hospital Paulistano ( Site 0406)Recruiting

São Paulo, 01321-001, Brazil

Hospital das Clinicas FMUSP ( Site 0402)Recruiting

São Paulo, 05403-010, Brazil

Cross Cancer Institute ( Site 0205)Recruiting

Edmonton, Alberta T6G 1Z2, Canada

Queen Elizabeth II Health Sciences Centre ( Site 0207)Recruiting

Halifax, Nova Scotia B3H 2Y9, Canada

Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0208)Recruiting

Hamilton, Ontario L8V 5C2, Canada

Lakeridge Health - The R.S. McLaughlin Durham Regional Cancer Centre (MDRCC) ( Site 0206)Recruiting

Oshawa, Ontario L1G 2B9, Canada

Sunnybrook Research Institute ( Site 0204)Recruiting

Toronto, Ontario M4N 3M5, Canada

Biocenter ( Site 0510)Recruiting

Concepción, Biobio 4070196, Chile

IC La Serena Research ( Site 0504)Recruiting

La Serena, Coquimbo Region 1720430, Chile

Oncocentro Valdivia ( Site 0506)Recruiting

Valdivia, Los Ríos Region 5112129, Chile

Centro de Estudios Clínicos SAGA ( Site 0508)Recruiting

Santiago, Region M. de Santiago 7500653, Chile

FALP ( Site 0501)Recruiting

Santiago, Region M. de Santiago 7500921, Chile

Clinica Inmunocel ( Site 0503)Recruiting

Santiago, Region M. de Santiago 7580206, Chile

Clínica RedSalud Vitacura ( Site 0512)Completed

Santiago, Region M. de Santiago 7650018, Chile

Bradfordhill ( Site 0502)Recruiting

Santiago, Region M. de Santiago 8420383, Chile

Centro de Investigaciones ( Site 0511)Recruiting

Viña del Mar, Valparaiso 2540488, Chile

Anhui Provincial Cancer Hospital ( Site 3124)Recruiting

Hefei, Anhui 230031, China

Peking University Third Hospital ( Site 3102)Recruiting

Beijing, Beijing Municipality 100096, China

Beijing Cancer Hospital ( Site 3101)Recruiting

Beijing, Beijing Municipality 100142, China

Chongqing Cancer Hospital ( Site 3113)Recruiting

Chongqing, Chongqing Municipality 400030, China

Fujian Provincial Cancer Hospital. ( Site 3119)Recruiting

Fuzhou, Fujian 350014, China

The First Affiliated Hospital of Xiamen University ( Site 3120)Recruiting

Xiamen, Fujian 361003, China

Sun Yat-sen University Cancer Center ( Site 3121)Recruiting

Guangzhou, Guangdong 510060, China

Zhujiang Hospital of Southern Medical University ( Site 3122)Recruiting

Guangzhou, Guangdong 510280, China

Affiliated Cancer Hospital of Guangxi Medical University ( Site 3123)Recruiting

Nanning, Guangxi 530021, China

The Affiliated Hospital of Guizhou Medical University ( Site 3112)Recruiting

Guiyang, Guizhou 550004, China

Hubei Cancer Hospital ( Site 3125)Recruiting

Wuhan, Hubei 430079, China

Affiliated Hospital of Nantong University ( Site 3117)Recruiting

Nantong, Jiangsu 226001, China

Jiangxi Cancer Hospital ( Site 3118)Recruiting

Nanchang, Jiangxi 330029, China

The First Hospital Of Jilin University ( Site 3103)Recruiting

Changchun, Jilin 130021, China

Shandong Cancer Hospital ( Site 3108)Recruiting

Jinan, Shandong 250117, China

LinYi Cancer Hospital ( Site 3104)Recruiting

Linyi, Shandong 276001, China

Fudan University Shanghai Cancer Center ( Site 3115)Recruiting

Shanghai, Shanghai Municipality 200032, China

Shanxi Cancer Hospital ( Site 3106)Recruiting

Taiyuan, Shanxi 030013, China

1st Affil Hosp of Med College of Xi'an Jiaotong University ( Site 3107)Recruiting

Xi’an, Shanxi 710061, China

Sichuan Cancer Hospital. ( Site 3111)Recruiting

Chengdu, Sichuan 610041, China

West China Hospital, Sichuan University ( Site 3110)Recruiting

Chengdu, Sichuan 610041, China

Institute of Hematology and Blood Diseases Hosp CAMS&PUMC ( Site 3105)Recruiting

Tianjin, Tianjin Municipality 301617, China

Yunnan Province Cancer Hospital ( Site 3109)Recruiting

Kunming, Yunnan 650118, China

The First Affiliated Hospital, Zhejiang Medical University ( Site 3116)Recruiting

Hangzhou, Zhejiang 310009, China

Hospital Pablo Tobon Uribe ( Site 0604)Recruiting

Medellín, Antioquia 050034, Colombia

Hospital Universitario San Ignacio ( Site 0607)Active, not recruiting

Bogotá, Bogota D.C. 110231, Colombia

IMAT S.A.S ( Site 0603)Recruiting

Montería, Departamento de Córdoba 230002, Colombia

Oncologos del Occidente ( Site 0601)Recruiting

Pereira, Risaralda Department 660001, Colombia

Fundación Valle del Lili ( Site 0602)Recruiting

Cali, Valle del Cauca Department 760032, Colombia

University College Hospital, Department of Haematology ( Site 1303)Recruiting

Aarhus, Central Jutland 8200, Denmark

Regionshospitalet Gødstrup ( Site 1301)Recruiting

Herning, Central Jutland 7400, Denmark

Aalborg University Hospital ( Site 1302)Recruiting

Aalborg, North Denmark 9000, Denmark

Odense Universitetshospital ( Site 1304)Recruiting

Odense, Region Syddanmark 5000, Denmark

Centre Antoine-Lacassagne ( Site 1514)Recruiting

Nice, Alpes-Maritimes 06189, France

Hopital Saint Louis, Centre Hospitalier de La Rochelle ( Site 1511)Recruiting

La Rochelle, Charente-Maritime 17000, France

CHU Dijon Bourgogne ( Site 1516)Recruiting

Dijon, Cote-d Or 21000, France

CHU GRENOBLE ALPES ( Site 1518)Recruiting

La Tronche, Isere 38700, France

Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 1512)Recruiting

Limoges, Limousin 87042, France

Centre Hospitalier Régional Metz Thionville - Hôpital de Mercy ( Site 1515)Recruiting

Metz, Moselle 57085, France

Centre Hospitalier de Dunkerque ( Site 1513)Recruiting

Dunkirk, Nord 59385, France

Centre Hospitalier Universitaire Estaing ( Site 1508)Recruiting

Clermont-Ferrand, Puy-de-Dome 63100, France

Centre Hospitalier de la Cote Basque ( Site 1509)Recruiting

Bayonne, Pyrenees-Atlantiques 64100, France

Centre Henri Becquerel ( Site 1517)Recruiting

Rouen, Seine-Maritime 76038, France

HIA Sainte Anne ( Site 1506)Recruiting

Toulon, Var 83800, France

Centre Hospitalier d'Avignon ( Site 1505)Recruiting

Avignon, Vaucluse 84000, France

CHD Vendee ( Site 1502)Recruiting

La Roche-sur-Yon, Vendee 85000, France

Institut Curie - site Saint-Cloud ( Site 1501)Recruiting

Saint-Cloud, Île-de-France Region 92210, France

Evangelismos General Hospital of Athens ( Site 1602)Recruiting

Athens, Attica 106 76, Greece

General Hospital of Athens "Laiko"-Hematology Department ( Site 1603)Recruiting

Athens, Attica 115 26, Greece

Attikon University General Hospital of Athens ( Site 1604)Recruiting

Athens, Attica 124 62, Greece

University General Hospital of Alexandroupoli ( Site 1601)Recruiting

Alexandroupoli, Evros 681 00, Greece

MEDI-K ( Site 0701)Recruiting

Guatemala City, 01009, Guatemala

CELAN,S.A ( Site 0702)Recruiting

Guatemala City, 01010, Guatemala

Cen Integral Onco Gastro y Hemato Onco Guatemala S.A. ( Site 0703)Recruiting

Guatemala City, 01010, Guatemala

Princess Margaret Hospital ( Site 3202)Recruiting

Hong Kong, Hong Kong

Queen Mary Hospital ( Site 3201)Recruiting

Hong Kong, Hong Kong

Semmelweis University-Belgyógyászati és Hematológiai Klinika ( Site 1703)Recruiting

Budapest, Hajdú-Bihar 1088, Hungary

Study CoordinatorContact

+3614591500

Debreceni Egyetem Klinikai Kozpont ( Site 1702)Recruiting

Debrecen, Hajdú-Bihar 4032, Hungary

Szabolcs Szatmár Bereg Vármegyei Oktatókórház ( Site 1704)Recruiting

Nyíregyháza, Szabolcs-Szatmár-Bereg 4400, Hungary

Tolna Vármegyei Balassa János Kórház ( Site 1710)Recruiting

Szekszárd, Tolna County 7100, Hungary

Orszagos Onkologiai Intezet ( Site 1705)Recruiting

Budapest, 1122, Hungary

Carmel Hospital ( Site 1903)Recruiting

Haifa, 3436212, Israel

Hadassah Medical Center ( Site 1901)Recruiting

Jerusalem, 9112001, Israel

Sourasky Medical Center ( Site 1904)Recruiting

Tel Aviv, 6423906, Israel

Poria Medical Center ( Site 1902)Recruiting

Tiberias, 15208, Israel

Fondazione IRCCS San Gerardo dei Tintori ( Site 2008)Recruiting

Monza, Lombardy 20900, Italy

IRCCS Crob ( Site 2002)Recruiting

Rionero in Vulture, Potenza 85028, Italy

Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO ( Site 2005)Recruiting

Palermo, Sicily 90146, Italy

INOC - Istituto Nazionale Oncologico Candiolo ( Site 2010)Recruiting

Candiolo, Torino 10060, Italy

AOU delle Marche Ospedali Riuniti di Ancona ( Site 2011)Recruiting

Ancona, 60126, Italy

Azienda Ospedaliera Spedali Civili di Brescia-Hemathology ( Site 2001)Recruiting

Brescia, 25123, Italy

IRCCS Ospedale San Raffaele ( Site 2012)Recruiting

Milan, 20132, Italy

IEO Istituto Europeo di Oncologia ( Site 2009)Recruiting

Milan, 20141, Italy

Azienda Ospedaliero Universitaria Maggiore della Carità ( Site 2004)Recruiting

Novara, 28100, Italy

Ospedale Santa Maria delle Croci ( Site 2006)Recruiting

Ravenna, 48121, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 2003)Recruiting

Roma, 00168, Italy

Nagoya University Hospital ( Site 3309)Recruiting

Nagoya, Aichi-ken 466-8560, Japan

National Cancer Center Hospital East ( Site 3303)Recruiting

Kashiwa, Chiba 277-8577, Japan

National Hospital Organization Shikoku Cancer Center ( Site 3321)Recruiting

Matsuyama, Ehime 791-0280, Japan

Kobe City Medical Center General Hospital ( Site 3318)Recruiting

Kobe, Hyōgo 650-0047, Japan

Kanazawa University Hospital ( Site 3308)Recruiting

Kanazawa, Ishikawa-ken 920-8641, Japan

Tokai University Hospital ( Site 3302)Recruiting

Isehara, Kanagawa 259-1193, Japan

Tohoku University Hospital ( Site 3301)Recruiting

Sendai, Miyagi 980-8574, Japan

Kindai University Hospital ( Site 3310)Recruiting

Sakai, Osaka 590-0197, Japan

Saitama Medical University Hospital ( Site 3305)Recruiting

Iruma-gun, Saitama 350-0495, Japan

Study CoordinatorContact

+81-49-276-1111

Juntendo University Hospital ( Site 3307)Recruiting

Bunkyo, Tokyo 113-8431, Japan

Study CoordinatorContact

+81-3-3813-3111

Tokyo Metropolitan Komagome Hospital ( Site 3323)Recruiting

Bunkyo, Tokyo 113-8677, Japan

Study CoordinatorContact

+81-3-3823-2101

University of Yamanashi Hospital ( Site 3320)Recruiting

Chūō, Yamanashi 409-3898, Japan

Chiba Cancer Center ( Site 3314)Recruiting

Chiba, 260-8717, Japan

Kyushu University Hospital ( Site 3313)Recruiting

Fukuoka, 812-8582, Japan

Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital ( Site 3322)Recruiting

Hiroshima, 730-8619, Japan

University Hospital,Kyoto Prefectural University of Medicine ( Site 3315)Recruiting

Kyoto, 602-8566, Japan

University of Miyazaki Hospital ( Site 3319)Recruiting

Miyazaki, 889-1692, Japan

Okayama University Hospital ( Site 3311)Recruiting

Okayama, 700-8558, Japan

Osaka Metropolitan University Hospital ( Site 3317)Recruiting

Osaka, 545-8586, Japan

Yamagata University Hospital ( Site 3312)Recruiting

Yamagata, 990-9585, Japan

Queen Elizabeth Hospital ( Site 3405)Recruiting

Kota Kinabalu, Sabah 88586, Malaysia

Sarawak General Hospital ( Site 3402)Recruiting

Kuching, Sarawak 93586, Malaysia

Hospital Miri ( Site 3403)Recruiting

Miri, Sarawak 98000, Malaysia

Sunway Medical Centre ( Site 3406)Recruiting

Petaling Jaya, Selangor 47500, Malaysia

Hospital Ampang ( Site 3404)Recruiting

Selangor Darul Ehsan, Selangor 68000, Malaysia

Study CoordinatorContact

+60342896559

CIMAB SA de CV ( Site 0807)Completed

Torreón, Coahuila 27000, Mexico

Grupo Ollin Care ( Site 0806)Completed

Pachuca, Hidalgo 42000, Mexico

Health Pharma Professional Research S.A. de C.V. ( Site 0801)Recruiting

Mexico City, Mexico City 03100, Mexico

Centro de Infusion Superare ( Site 0804)Recruiting

Mexico City, Mexico City 03104, Mexico

Centro de Investigacion Clinica Chapultepec ( Site 0803)Recruiting

Morelia, Michoacán 58260, Mexico

Hospital Universitario ""Dr. Jose Eleuterio Gonzalez"" ( Site 0802)Recruiting

Monterrey, Nuevo León 64460, Mexico

Centro de Investigacion Clinica de Oaxaca ( Site 0805)Recruiting

Oaxaca City, 68020, Mexico

Albert Schweitzer Ziekenhuis ( Site 2103)Recruiting

Dordrecht, South Holland 3318 AT, Netherlands

Meander Medisch Centrum ( Site 2101)Recruiting

Amersfoort, Utrecht 3813 TZ, Netherlands

Clínicas AUNA Sede Chiclayo ( Site 0904)Recruiting

Chiclayo, Lambayeque 14001, Peru

INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 0901)Active, not recruiting

Surquillo, Muni Metro de Lima 15038, Peru

Clínica San Felipe ( Site 0906)Recruiting

Lima, 15072, Peru

Hospital Nacional Edgardo Rebagliati Martins ( Site 0903)Recruiting

Lima, 15072, Peru

Hospital Nacional Dos De Mayo ( Site 0905)Recruiting

Lima, 15087, Peru

Pratia Onkologia Wroclaw ( Site 2211)Recruiting

Wroclaw, Lower Silesian Voivodeship 50-019, Poland

Uniwersytecki Szpital Kliniczny nr 1 w Lublinie ( Site 2202)Recruiting

Lublin, Lublin Voivodeship 20- 081, Poland

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 2201)Completed

Warsaw, Masovian Voivodeship 02-781, Poland

Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku ( Site 2210)Recruiting

Słupsk, Pomeranian Voivodeship 76-200, Poland

Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 2208)Recruiting

Gliwice, Silesian Voivodeship 44-102, Poland

Pratia Onkologia Katowice ( Site 2204)Recruiting

Katowice, Silesian Voivodeship 40-519, Poland

Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko-Mazurskim Centrum Onko ( Site 2205)Recruiting

Olsztyn, Warmian-Masurian Voivodeship 10-228, Poland

Unidade Local de Saude de Braga - Hospital de Braga ( Site 2306)Recruiting

Braga, 4710-243, Portugal

Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 2308)Recruiting

Lisbon, 1649-035, Portugal

Instituto Portugues de Oncologia Do Porto Francisco Gentil E.P.E. ( Site 2302)Recruiting

Porto, 4200-072, Portugal

Auxilio Mutuo Cancer Center ( Site 1001)Recruiting

San Juan, 00918, Puerto Rico

BRCR Global Puerto Rico - Caribbean Cancer Care ( Site 1003)Recruiting

Yauco, 00698, Puerto Rico

Spitalul Clinic Colțea ( Site 2401)Completed

Bucharest, Bucharest 030171, Romania

Institutul Oncologic Cluj ( Site 2404)Recruiting

Cluj-Napoca, Cluj 4003437, Romania

Centrul de Diagnostic si Tratament Oncologic Brasov ( Site 2402)Completed

Brasov, 500052, Romania

Spital Judetean Sibiu ( Site 2405)Recruiting

Sibiu, 557260, Romania

National University Hospital ( Site 3702)Recruiting

Singapore, Central Singapore 119074, Singapore

National Cancer Centre Singapore ( Site 3701)Recruiting

Singapore, Central Singapore 168583, Singapore

LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 2506)Recruiting

Pretoria, Gauteng 0181, South Africa

Netcare Pretoria East Hospital ( Site 2502)Recruiting

Pretoria, Gauteng 0181, South Africa

Haemalife ( Site 2501)Recruiting

Cape Town, Western Cape 7580, South Africa

Groote Schuur Hospital ( Site 2504)Recruiting

Cape Town, Western Cape 7925, South Africa

National Cancer Center- Center for Hemotologic malignancy ( Site 3806)Recruiting

Goyang-si, Kyonggi-do 10408, South Korea

Pusan National University Hospital ( Site 3804)Recruiting

Busan, Pusan-Kwangyokshi 49241, South Korea

Chungnam National University Hospital ( Site 3801)Recruiting

Daejeon, Taejon-Kwangyokshi 35015, South Korea

Severance Hospital, Yonsei University Health System ( Site 3802)Completed

Seoul, 03722, South Korea

Asan Medical Center ( Site 3803)Recruiting

Seoul, 05505, South Korea

Samsung Medical Center ( Site 3807)Completed

Seoul, 06351, South Korea

St.Mary's H., Youido ( Site 3805)Recruiting

Seoul, 07345, South Korea

Hospital Universitario Virgen Macarena ( Site 2608)Recruiting

Seville, Andalusia 41009, Spain

ICO L Hospitalet ( Site 2601)Recruiting

L'Hospitalet de Llobregat, Barcelona 08908, Spain

H. Insular de Gran Canaria ( Site 2606)Recruiting

Las Palmas de Gran Canaria, Las Palmas 35016, Spain

Hospital Universitario Puerta de Hierro ( Site 2615)Recruiting

Majadahonda, Madrid 28222, Spain

Hospital de Cabuenes ( Site 2613)Recruiting

Gijón, Principality of Asturias 33394, Spain

Hospital General Universitario Dr. Balmis ( Site 2604)Recruiting

Alicante, Valenciana, Comunitat 03010, Spain

Hospital del Mar ( Site 2610)Recruiting

Barcelona, 08003, Spain

HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON ( Site 2614)Recruiting

Madrid, 28007, Spain

Hospital General Universitario 12 de Octubre ( Site 2605)Recruiting

Madrid, 28041, Spain

Hospital Universitario La Paz ( Site 2611)Recruiting

Madrid, 28046, Spain

Hospital Virgen de la Victoria ( Site 2609)Recruiting

Málaga, 29010, Spain

Hospital Universitario Miguel Servet ( Site 2607)Completed

Zaragoza, 50009, Spain

Kantonspital Baden ( Site 2703)Recruiting

Baden, Canton of Aargau 5404, Switzerland

Cantonal Hospital St.Gallen-Oncology & Hematology ( Site 2702)Recruiting

Sankt Gallen, Canton of St. Gallen 9000, Switzerland

Ospedale Regionale Bellinzona e Valli ( Site 2701)Recruiting

Bellinzona, Canton Ticino 6501, Switzerland

Ospedale Italiano Lugano (OIL) ( Site 2705)Recruiting

Lugano, Canton Ticino 6900, Switzerland

Chang Gung Memorial Hospital - Linkou Branch ( Site 3903)Recruiting

Taoyuan City, Taoyuan 333, Taiwan

Chang Gung Memorial Hospital at Kaohsiung ( Site 3905)Recruiting

Kaohsiung City, 83301, Taiwan

National Cheng Kung University Hospital ( Site 3902)Recruiting

Tainan, 704, Taiwan

National Taiwan University Hospital ( Site 3901)Recruiting

Taipei, 10002, Taiwan

Mackay Memorial Hospital ( Site 3908)Completed

Taipei, 10449, Taiwan

Tri-Service General Hospital ( Site 3906)Recruiting

Taipei, 114, Taiwan

Faculty of Medicine Siriraj Hospital ( Site 4001)Completed

Bangkoknoi, Bangkok 10700, Thailand

Chulalongkorn University ( Site 4003)Recruiting

Pathumwan, Bangkok 10330, Thailand

Study CoordinatorContact

+6622564000

Maharaj Nakorn Chiang Mai Hospital ( Site 4002)Recruiting

Muang, Chiang Mai 50200, Thailand

Study CoordinatorContact

+6653935488

Ondokuz Mayıs Universitesi ( Site 2806)Recruiting

Korfez Mahallesi, Samsun 55270, Turkey (Türkiye)

Study CoordinatorContact

+905052722289

Namık Kemal University Medical Faculty ( Site 2807)Recruiting

Suleymanpasa, Tekirdas 59030, Turkey (Türkiye)

Study CoordinatorContact

+905326347632

Baskent Universitesi Adana Dr. Turgut Noyan UAM ( Site 2809)Completed

Adana, 01120, Turkey (Türkiye)

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 2803)Recruiting

Ankara, 06200, Turkey (Türkiye)

Hacettepe Universite Hastaneleri ( Site 2810)Recruiting

Ankara, 06230, Turkey (Türkiye)

Ankara University Faculty of Medicine ( Site 2801)Recruiting

Ankara, 06620, Turkey (Türkiye)

Antalya Egitim ve Arastirma Hastanesi ( Site 2805)Completed

Antalya, 7100, Turkey (Türkiye)

Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi ( Site 2804)Recruiting

Istanbul, 34722, Turkey (Türkiye)

MNPE ClinCenter of Oncology,Hematology,Transplantology and Palliative Care of CherkasyRegCouncil ( Site 2904)Recruiting

Cherkasy, Cherkasy Oblast 18009, Ukraine

Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council" ( Site 2906)Recruiting

Ivano-Frankivsk, Ivano-Frankivsk Oblast 76008, Ukraine

Khmelnytskyi Regional Hospital ( Site 2907)Recruiting

Khmelnytskiy, Khmelnytskyi Oblast 29000, Ukraine

Study CoordinatorContact

+380382649001

Institute of Blood Pathology and Transfusion Medicine AMS Ukraine ( Site 2903)Recruiting

Lviv, Lviv Oblast 79057, Ukraine

SNPE National Cancer Institute ( Site 2902)Recruiting

Kyiv, 03022, Ukraine

Universal Clinic Oberig ( Site 2908)Completed

Kyiv, 03057, Ukraine

SI National Research Center of Radiation Medicine, Hematology, Oncology ( Site 2901)Completed

Kyiv, 03115, Ukraine