Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
After a spinal injection, blood pressure might drop for a short time, similar to what happens with general anesthesia. This drop can be different for each person. An anesthesiologist will use medicine to bring the blood pressure back to normal. If this drop could be predicted in advance, it would help the anesthesiologist treat it faster, making the procedure even safer and preventing side effects like dizziness or nausea.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hypotensive patients | Patients who developed hypotension after the induction of spinal anesthesia. |
| |
| Normotensive patients | Patients who did not develop hypotension after the induction of spinal anesthesia. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Carotid ultrasound measurement | Diagnostic Test | Pulsed-wave Doppler acquisition of the carotid artery. One acquisition will be made with the slow-speed setting (33 mm/s) and one with the medium-speed setting (66 mm/s). |
| Measure | Description | Time Frame |
|---|---|---|
| Determine the predictive value of pre-anesthetic carotid parameters to predict spinal anesthesia-induced hypotension. | To determine the predictive value of pre-anesthetic corrected carotid flow time (ccFT) and peak velocity variation values for hypotension after induction of spinal anesthesia. | Prior to surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between carotid parameters and blood pressure. | To determine the correlation between the pre-anesthetic corrected carotid flow time (ccFT) and peak velocity variation on one hand and the maximal changes in systolic and mean arterial blood pressure after spinal anesthesia on the other hand. | Trough study completion, an average of 30 minutes. |
| Measure | Description | Time Frame |
|---|---|---|
| Intra-observer and inter-observer reproducibility of carotid Doppler parameters. | To determine the intra-observer and inter-observer reproducibility of Doppler parameters derived by two experienced sonographers. | Prior to surgery. |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Adult patients scheduled for elective surgery under spinal anesthesia.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Arthur Bouwman, Professor | Catharina Ziekenhuis | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Catharina Ziekenhuis | Eindhoven | North Brabant | 5623 EJ | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Result | J. van Houte. The corrected carotid artery flow time and carotid peak velocity variation do not predict spinal anesthesia-induced hypotension: A prospective observational study. JCA Advances. 2024; 1: 1-8. | ||
| 40057795 | Derived | de Boer EC, van Houte J, Fernandes CD, Bakkes T, Muehlsteff J, Bouwman RA, Mischi M. Exploring the predictive value of carotid Doppler ultrasound and clinical features for spinal anesthesia-induced hypotension: a prospective observational study. Perioper Med (Lond). 2025 Mar 8;14(1):26. doi: 10.1186/s13741-025-00508-w. |
Not provided
Not provided
Patients did not give consent that their data would be used in studies other than spinal anesthesia-induced hypotension prediction.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D055986 | Vital Signs |
| D000775 | Anesthesia, Spinal |
| ID | Term |
|---|---|
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D000765 | Anesthesia, Conduction |
Not provided
Not provided
Not provided
Not provided
Not provided
| Vital sign measurement | Diagnostic Test | Measurement of noninvasive blood pressure, at different time points before and after the induction of spinal anesthesia. |
|
| Spinal anesthesia | Drug | Following the standard of care, the patients received spinal anesthesia. The type and dosage of the local anesthetic were at the discretion of the treating anesthesiologist. |
|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |