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The goal of this observational study is to learn about the long-term prognostic of coronary microvascular dysfuction in Patients Treated with Rotational Atherectomy During Percutaneous Coronary Intervention.
The main question it aims to answer is: Does the coronary microvascular dysfunction impact the outcomes in Patients Treated with Rotational Atherectomy During Percutaneous Coronary Intervention.
Participants will answer survey questions about their clinical outcomes for 2 years by telephone.
This study was a retrospective, multicenter observational investigation and approved by the local Human Research Ethics Committee and conducted in accordance with the principles outlined in the Helsinki Declaration.Patients aged 18 years or older who had severe coronary calcification and underwent successful RA during PCI were eligible for inclusion in the study. Exclusion criteria included target vessel was chronic total occlusion, poor angiographic image quality, failed RA and RA not used for severe coronary calcification.
Angiography-derived index of microcirculatory resistance was measured in the target vessel treated with RA pre-PCI and post-PCI and blinded and performed by an independent core laboratory.The follow-up entailed the utilization of a multipronged approach, encompassing clinic visits, medical record reviews and telephone contacts.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Coronary microvascular dysfunction | angio-IMR>=25 | ||
| Non-Coronary microvascular dysfunction | Angio-IMR<25 |
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| Measure | Description | Time Frame |
|---|---|---|
| major adverse cardiac events | the composite of cardiac death, myocardial reinfarction, target vessel revascularization, and readmission for unstable angina | 24 months after PCI |
| Measure | Description | Time Frame |
|---|---|---|
| target vessel failure | composed of cardiac death, target vessel myocardial infarction, target vessel revascularization | 24 months after PCI |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged 18 years or older who had severe coronary calcification and underwent successful RA during PCI
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| 88 Jiefang Road | Hangzhou | Zhejiang | 310009 | China |
undecided
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
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