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To investigate the molecular mechanism of raspberry ketone on regulating obesity, the investigators studied the effect of raspberry ketone intake on FGF21 in plasma.
The age of the volunteers were 18-60 years old, both male and female, without diabetes, hypertension and other diseases.
After ingestion of raspberry ketone (500mg), 2ml of blood was collected at 0 hours, 3 hours and 6 hours , and the FGF21 content in plasma was measured using a commercial reagent kit.
In addition, the investigators also studied the effect of raspberry ketone intake on energy metabolism 0 hours, 0.5 hours, 3 hours and 6 hours after consuming raspberry ketone (500mg).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Human administrated with raspberry ketone | Experimental |
| |
| Human administrated with placebo | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Raspberry ketone | Dietary Supplement | Human consumed 500mg of raspberry ketone |
|
| Measure | Description | Time Frame |
|---|---|---|
| Impact of raspberry ketone consumption on plasma FGF21 level | Through study completion, an average of 1 year | |
| Impact of raspberry ketone consumption on energy expenditure | The oxygen consumption, heart rate, carbon dioxide production were measured | Through study completion, an average of 1 year |
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Inclusion Criteria:
No drugs were taken before the human study
Exclusion Criteria:
Patients with hypertension
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nanchang University | Nanchang | Jiangxi | 330047 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23601452 | Background | Lopez HL, Ziegenfuss TN, Hofheins JE, Habowski SM, Arent SM, Weir JP, Ferrando AA. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. J Int Soc Sports Nutr. 2013 Apr 19;10(1):22. doi: 10.1186/1550-2783-10-22. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D003920 | Diabetes Mellitus |
| D065626 | Non-alcoholic Fatty Liver Disease |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| C035522 | raspberry ketone |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| D005234 | Fatty Liver |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |