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| Name | Class |
|---|---|
| Montreal General Hospital | OTHER |
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Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function of individuals post-bariatric surgery.
The objective of this study is to analyze the relationships between changes in body composition, nutrition and protein intake, and muscle function after bariatric surgery to further our understanding of the nutritional needs of patients after bariatric surgery.
We intend to recruit around 75 participants, men and women, aged between 18 and 65 years. Participants will be recruited from the Bariatric Surgery Clinic, McGill University Health Center.
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| Measure | Description | Time Frame |
|---|---|---|
| Change in weight | Overall weight loss (kg) | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Change in BMI | Height and weight will be measured and combined to report BMI (kg/m^2). | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Change in fat mass | Body composition is measured by dual-energy x-ray absorptiometry. | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Change in overall body fat percentage | Body composition is measured by dual-energy x-ray absorptiometry. | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Resting Energy Expenditure | Resting energy expenditure will be measured in a fasted state by indirect calorimetry. The volume of oxygen and carbon dioxide and water vapor pressure will be taken into consideration to calculate the resting energy expenditure. | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Substrate Oxidation | Substrate oxidation will be measured in a fasted state by indirect calorimetry. The volume of oxygen, carbon dioxide, and water vapor pressure will be taken into consideration to calculate the respiratory exchange ratio. | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Nurition and Protein Intake |
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Inclusion Criteria:
Exclusion Criteria:
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Individuals living with obesity to undergo primary bariatric surgery from the Montreal area. Individuals to be recruited from the Montreal General Hospital Bariatric Clinic.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sylvia Santosa, PhD, R.D. | Contact | 514-848-2424 | x5841 | s.santosa@concordia.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Montreal General Hospital (MUHC) | Recruiting | Montreal | Quebec | H3G 1A4 | Canada |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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Blood and urine samples for the purpose of further laboratory analysis.
A 3-day food journal and a 24-hour food recall will measure the nutritional profile (protein intake). A 24-hour urine sample will be used to measure urinary nitrogen concentration. |
| Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| Hormone and Inflammatory Marker Assays | The inflammatory cytokines, chemokines, and adipokines in blood will be measured using Enzyme-Linked Immunosorbent Assay (ELISA). | Baseline (pre-operation), and at 3-months and 6-months post-operation. |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |