HIV and Multi-Drug Resistant Tuberculosis: a Study on Clinical Outcomes

HIV Infection Accompanied by Multi-Drug Resistant Tuberculosis: a Decadal Systematic Review and Meta-Analysis

This study aims to investigate the relationship between HIV infection and multi-drug resistant tuberculosis (MDR-TB) among affected individuals in Zahedan, Iran. It will involve a detailed analysis of patient demographics, clinical characteristics, and treatment outcomes to enhance understanding of this co-infection. The findings may inform better treatment strategies and healthcare policies for managing these diseases in similar populations.

Inclusion Criteria:

• Adults (aged 18 years and older) diagnosed with both HIV and multi-drug-resistant tuberculosis (MDR-TB).
• Studies published in peer-reviewed journals.
• Studies that provide data on the co-occurrence of HIV and MDR-TB.
• Participants from diverse geographical regions to enhance generalizability.
• Studies with clear definitions of MDR-TB according to WHO guidelines.

Exclusion Criteria:

• Studies that focus solely on drug-susceptible tuberculosis without MDR-TB.
• Studies involving pediatric populations (under 18 years of age).
• Non-original research such as reviews, editorials, and commentaries.
• Studies lacking sufficient data on the co-occurrence of HIV and MDR-TB.
• Studies that do not adhere to ethical guidelines for human subjects or lack appropriate ethical approvals.