Concurrent physical exercise is the method of combining strength and endurance that can be worked with in one session or in an exercise program. Therefore, the researchers seek to implement it in patients suffering from chronic renal failure with hemodialysis therapy and see if concurrent physical exercise improves quality of life levels and at the same time see the response of physical fitness, body composition and biochemistry.

Introduction: The performance of physical exercise has positive effects in terms of quality of life, but when it is not performed consistently it triggers a sedentary lifestyle, which is reflected in overweight and obesity, in addition to developing chronic noncommunicable diseases, propitiating chronic kidney disease, which although, hereditary and environmental factors are also present in this pathology and as the disease progresses, chronic renal failure develops. Objective: To analyze the effect of a concurrent physical exercise program on quality of life in patients with chronic renal failure undergoing hemodialysis. Methods: Uncontrolled clinical trial in which a concurrent physical exercise program will be carried out for 6 weeks, performing physical evaluations such as 6-minute walk and manual strength by dynamometer, application of SF-36 questionnaires, measurement of urea, glucose, creatinine and albumin, in addition to analyzing body composition by electrical bioimpedance.

Inclusion Criteria:

• Patients who are cared for at the State Hemodialysis Center.
• Receive hemodialysis treatment 3 times per week.
• Sign the informed consent form.

Exclusion Criteria:

• Patients under 18 years of age.
• Patients with a history of fracture at less than 2 months of evolution.
• Patients with any rheumatologic disease (lupus or rheumatoid arthritis).
• Prostrate patients.
• Amputee patients.
• Positive patients (HIV).
• Uncontrolled comorbidities.

Elimination.

• Patients who make their voluntary withdrawal from the project. Inability to engage in physical exercise.
• Death.

the plan to share information with other researchers is through the publication of different articles that can be extracted from the research.

The information will be available as of August 2025.

In order to have access to these data, other researchers must be performing the same methodological design, so there is no point in sharing it with a different study design.

The masking consists of the investigator not performing the physical evaluations.