Effect of Coenzyme Q10 Administration on Polycystic Ovary Syndrome

The Effect of Coenzyme Q10 Supplementation on Oxidative Stress, Inflammation and Hyperandrogenism in Women with Polycystic Ovary Syndrome

The goal of this clinical trial is to determine the effects of coenzyme Q10 supplementation on oxidative stress, inflammation and hyperandrogenism in women with polycystic ovary syndrome. The main questions it aims to answer are:

Does Coenzyme Q10 alter oxidative stress, inflammation and hyperandrogenism in women with Polycystic ovary syndrome.

Participants will take Coenzyme Q10 200mg, once daily for a period of 3 months. The participants will be reassessed after 12 weeks by measuring Malondialdehyde MDA, C-reactive protein CRP, Sex hormone binding globulin SHBG.

Inclusion Criteria:

• Married Patients that presented with anovulatory infertility due to PCOS.
• Unmarried Patients that presented with symptoms due to PCOS
• All patients should fulfill Rotterdam criteria for PCOS

Exclusion Criteria:

• Male factor infertility ( oligospermia or aspermia)
• Tubal factor infertility (abnormal hysterosalpingography)
• Diabetes mellitus, thyroid dysfunction, cardiovascular diseases, impairment of hepatic and renal function
• Autoimmune and Inflammatory disorders
• Abnormal serum prolactin level
• Smokers
• Alcoholic beverage use
• Use of anti diabetic, anti-obesity drugs, insulin or vitamin and mineral supplements